20.500.12556/DiRROS-29891 Chronic vulvar itch diagnostic and therapeutic challenges Vulvar pruritus refers to itching affecting the skin and mucosal surfaces of the external genital and perineal regions. It is most frequently associated with infections, inflammatory skin disorders, or neoplastic conditions. Due to the distinctive anatomical and physiological features of the anogenital area, clinical manifestations in this region are often subtle or atypical, which can complicate both diagnosis and management. Because vulvar itch can be highly distressing, timely identification and appropriate intervention are crucial for improving patient quality of life. A comprehensive clinical approach is essential when evaluating patients with vulvar pruritus. This includes a detailed medical history, focused physical examination, and relevant diagnostic testing. Management should involve elimination of contributing or exacerbating factors and treatment directed at the underlying cause. This review article discusses the common causes of vulvar pruritus, emphasizing the diagnostic approach and outlining current treatment strategies. The importance of an individualized patient-centered management plan is emphasized. vulvar itch pruritus diagnosis treatment barrier function srbež vulve srbečica diagnoza zdravljenje pregradna funkcija kože true false true Združenje slovenskih dermatovenerologov Angleški jezik Slovenski jezik Na spletni strani revije navedeno: Acta Dermatovenerologica Alpina, Pannonica et Adriatica (ISSN 1318-4458) is an open access medical journal published quarterly by the Association of Slovenian Dermatovenerologists (https://acta-apa.mf.uni-lj.si/index.php); Authors publishing in our journal retain copyright of their work under the Creative Commons Attribution License (CC BY 4.0). This license allows unrestricted use, distribution, and reproduction of the work in any medium, provided the original author(s) and copyright holder(s) are appropriately credited, and the original publication in the journal is properly cited, following established academic practices (https://acta-apa.mf.uni-lj.si/submissions.php). Neznano 2026-06-09 08:37:44 2026-06-09 09:06:45 2026-07-05 23:18:48 0000-00-00 00:00:00 2025 0 Ljubljana 0 str. 123-131 issue 3 Vol. 34 Sep. 2025 0000-00-00 Zaloznikova Objavljeno NiDoloceno 2025-06-20 2025-07-31 2025-09-01 616.5 1318-4458 10.15570/actaapa.2025.25 251408131 https://acta-apa.mf.uni-lj.si/journals/acta-dermatovenerol-apa/papers/10.15570/actaapa.2025.25/actaapa.2025.25.pdf 1 b90b036d-63cd-11f1-9215-001a4af901a5 https://dirros.openscience.si/Dokument.php?lang=slv&id=44990 RAZ_Trcko_Katarina_2025.pdf RAZ_Trcko_Katarina_2025.pdf 1 A41460B4AC6874559CD6F192C5D5C5BE 8f75d1dc12e1aad72ab7c037e7cf84156af7f65e5df2d7c49f49aa7a59b28703 d296a52d-63d1-11f1-9215-001a4af901a5 https://dirros.openscience.si/Dokument.php?lang=slv&id=45019 Združenje slovenskih dermatovenerologov Acta dermatovenerologica Alpina, Panonica et Adriatica 0 0 0