20.500.12556/DiRROS-29755 Navigating intraductal papillary mucinous neoplasm management through fukuoka consensus vs. european evidence-based guidelines on pancreatic cystic neoplasms a study on two European centers This study addresses the critical need for the accurate diagnosis and management of intraductal papillary mucinous neoplasms (IPMNs), which are pancreatic cystic neoplasm types holding a substantial potential for malignancy. It evaluates the diagnostic effectiveness of the Fukuoka consensus guidelines and the European evidence-based guidelines in detecting high-grade dysplasia/invasive carcinoma in IPMNs, utilizing a retrospective analysis of 113 patients from two European medical centers. The methods include a comparative analysis of clinical, radiological, and endoscopic ultrasonography data, alongside an assessment of guideline-driven diagnostic performance. The results demonstrate that both guidelines offer similar accuracy in identifying severe disease stages in IPMNs, with certain clinical markers-such as jaundice, solid mass presence, and an increase in CA 19-9 levels-being pivotal in predicting the need for surgical intervention. This study concludes that while both guidelines provide valuable frameworks for IPMN management, there is an inherent need for further research to refine these protocols and improve patient-specific treatment strategies. This research contributes to the ongoing discourse on optimizing diagnostic and treatment paradigms for pancreatic cystic neoplasms, aiming to enhance clinical outcomes and patient care in this challenging medical field. IPMN Serbia Slovenia true false true Angleški jezik Ni določen Neznano 2026-06-04 13:50:22 2026-06-04 13:50:22 2026-06-05 04:05:59 0000-00-00 00:00:00 2024 0 0 Nasl. z nasl. zaslona; Opis vira z dne 15. 7. 2024; article no.2156; str. 1-16 no. 11 Vol. 16 2024 0000-00-00 Zaloznikova Objavljeno NiDoloceno 0000-00-00 0000-00-00 0000-00-00 61 2072-6694 10.3390/cancers16112156 201790211 RAZ_Djordjevic_Vladimir_2024.pdf RAZ_Djordjevic_Vladimir_2024.pdf 1 ABA8B4F0CBD2183BBB1A472D4E39C5CA a940ed53945dc1751a6d827e26651296e854879864be7241c93b772b361108e0 e7586626-600b-11f1-9215-001a4af901a5 https://dirros.openscience.si/Dokument.php?lang=slv&id=44724 https://www.mdpi.com/2072-6694/16/11/2156 0 93225656-600b-11f1-9215-001a4af901a5 https://dirros.openscience.si/Dokument.php?lang=slv&id=44723 Univerzitetni klinični center Ljubljana 0 0 0