20.500.12556/DiRROS-29723 Cardiac troponins I and T as biomarkers of cardiomyocyte injury - advantages and disadvantages of each Measurement of cardiac troponin in serum is an essential part of diagnosing myocardial infarction in the emergency department. The guidelines suggest that high-sensitivity techniques should be used for measuring cardiac troponin I (cTnI) or cardiac troponin T (cTnT). The aim of our study was to correlate the values of both troponins, and to ascertain which type of troponin is more in agreement with the diagnosis. The patients were classified into four groups: 43 patients in non-ST-elevation myocardial infarction (NSTEMI), 7 in ST-elevation myocardial infarction (STEMI), 48 in Type 2 myocardial infarction, and 21 in the control group. A significant correlation between cTnI and cTnT was found in the NSTEMI (r = 0.70) and Type 2 (r = 0.75) groups while in the control group there was no association (r = −0.06). The ratios of cTnI and cTnT relative to their cut-off values were lower in Type 2 myocardial infarction compared to NSTEMI. This difference can be attributed to the pathophysiology of these two types of heart conditions. The ratio in the NSTEMI group was higher in female than in male patients (53.3 vs. 24.6 ng/L); the same difference was found for the ratio of cTnT (20.8 vs. 13.1 ng/L). In the same manner, the ratios in the Type 2 group were higher in female than in male patients for cTnI (25.6 vs. 12.7 ng/L) as well as for cTnT (19.0 vs. 6.73 ng/L). These differences could be due to biological differences, but they could also be influenced by other factors contributing to different damage responses. cardiac troponin I cardiac troponin T myocardial infarction srčni troponin I srčni troponin T true false true Angleški jezik Slovenski jezik Neznano 2026-06-03 15:02:19 2026-06-03 15:02:19 2026-06-04 04:04:46 0000-00-00 00:00:00 2024 0 0 Nasl. z nasl. zaslona; Opis vira z dne 10. 7. 2024; Št. članka 6007; str. 1-12 iss. 14, ǂart. ǂ6007 Vol. 14 2024 0000-00-00 Zaloznikova Objavljeno NiDoloceno 0000-00-00 0000-00-00 0000-00-00 616-074:616.127-005.8 2076-3417 10.3390/app14146007 201335299 RAZ_Osredkar_Josko_2024.pdf RAZ_Osredkar_Josko_2024.pdf 1 53675CB1FCCD511FB4EDEB99D27767C6 01dd86571ce1f936e3080fd4f94241b295b67f34984e29c27b6113ecaf88016f 98af47cd-5f4c-11f1-9215-001a4af901a5 https://dirros.openscience.si/Dokument.php?lang=slv&id=44661 https://www.mdpi.com/2076-3417/14/14/6007 1 74e16aa6-5f4c-11f1-9215-001a4af901a5 https://dirros.openscience.si/Dokument.php?lang=slv&id=44660 Univerzitetni klinični center Ljubljana 0 0 0