20.500.12556/DiRROS-29277 Garje pri otrocih in mladostnikih Scabies in children and adolescents Garje (scabies) so nalezljiva parazitska kožna bolezen, ki jo povzroča pršica Sarcoptes scabiei var. hominis. Prenašajo se predvsem s tesnim stikom kože na kožo, redkeje posredno preko okuženega perila ali posteljnine. Najpogosteje zbolevajo dojenčki in otroci, v primeru prisotnosti scabies norvegica (crustosa) pa obolevajo osebe z oslabljenim imunskim sistemom. V zadnjih letih v Evropi in Sloveniji opažamo izrazit porast pojavnosti garij, tudi v okoljih z ustrezno higieno. Bolezen se kaže z značilnim srbenjem, najizrazitejšim ponoči, ter s tipičnimi papulami v parih, pogosto razpraskanimi in pokritimi s krasto, na področju tanjše, mehke in neporaščene kože z manjšim izločanjem loja. Pri dojenčkih so lahko prizadeti tudi obraz, lasišče, dlani in podplati. Razvijejo se lahko tudi skabični granulomi in infantilna akropustuloza. Diagnoza temelji na klinični sliki, dermatoskopiji in mikroskopskem dokazu pršic ali njihovih produktov. Zdravljenje vključuje lokalno uporabo 5-odstotnega permetrina kot zdravila prve izbire, pri odpornih oblikah ali posebnih indikacijah pa poleg zamenjave lokalne terapije lahko tudi peroralno zdravljenje z ivermektinom. Pomembna sta sočasno zdravljenje vseh družinskih članov oz. oseb, s katerimi je bil otrok v stiku, in dosledno izvajanje higienskih ukrepov. V zadnjem času poročajo o vse pogostejši neučinkovitosti svetovane terapije zaradi nepravilne uporabe in razvoja rezistentnosti pršic na te ukrepe, kar poudarja potrebo po zgodnjem prepoznavanju bolezni, ustreznem zdravljenju in preventivi. Scabies is a contagious parasitic skin disease caused by the mite Sarcoptes scabiei var. hominis. Transmission occurs mainly through close skin-to-skin contact and, less commonly, indirectly via contaminated clothing or bedding. Infants and children are most commonly affected, and in the case of scabies norvegica, people with weakened immune systems. In recent years, a marked increase in incidence has been observed across Europe and Slovenia, including in settings with adequate hygiene. The disease is characterized by intense pruritus, most pronounced at night, and with typical papules in pairs, often scratched and covered with scabs, in areas of thinner, soft and hairless skin with less sebum secretion. In infants, the face, scalp, palms, and soles may also be involved. Scabies granulomas and infantile acropustulosis may also develop. Diagnosis is based on the clinical presentation, dermatoscopy, and microscopic identification of mites or their products. Treatment includes topical application of 5% permethrin as the first-line drug, but in resistant forms or for special indications, oral ivermectin can be used in addition to replacing topical therapy. Simultaneous treatment of all family members or contacts and consistent implementation of hygiene measures are important. Recently, there have been reports of increasing ineffectiveness of recommended therapy due to incorrect use and development of mite resistance, which emphasizes the need for early recognition of the disease, appropriate treatment and prevention. parazitne bolezni garje scabies otroci klinična slika zdravljenje parasitic diseases scabies children clinical picture treatment true false true Slovenski jezik Angleški jezik Na spletni strani revije navedeno "Slovenska pediatrija je revija z odprtim dostopom, vsi objavljeni prispevki so prosto in takoj po objavi dostopni za deljenje in uporabo ob ustreznem citiranju originalnih avtorjev in vira (Licenca CC-BY-NC 4.0)." (https://www.slovenskapediatrija.si/sl-si/, 6. 5. 2026) Neznano 2026-05-06 08:50:45 2026-05-06 08:50:45 2026-05-07 03:51:12 0000-00-00 00:00:00 2026 0 0 Besedilo v slov.; str. 38-44 št. 1 Letn. 33 2026 0000-00-00 Zaloznikova Objavljeno NiDoloceno 0000-00-00 0000-00-00 0000-00-00 616-053.2 1318-4423 10.38031/slovpediatr-2026-1-06 277103107 RAZ_Zupan_Amadea_2026.pdf RAZ_Zupan_Amadea_2026.pdf 1 35164FBDC5EA46A517627F8CF348590B da86a91b6e00405dd9f5dd00e4ba297bfdc31acaaa4c30c5f04e890f35da7188 0a417fad-4918-11f1-8a5a-001a4af901a5 https://dirros.openscience.si/Dokument.php?lang=slv&id=43818 https://www.slovenskapediatrija.si/clanek?revija=1070&clanek=2500 1 e9531cbf-4917-11f1-8a5a-001a4af901a5 https://dirros.openscience.si/Dokument.php?lang=slv&id=43817 Univerzitetni klinični center Ljubljana 0 0 0