20.500.12556/DiRROS-29266 Clinical outcomes after hysteroscopic removal of retained products of conception with or without prior uterine artery embolization Purpose: Retained products of conception (RPOC) are a common complication after pregnancy. While hysteroscopic resection is the standard treatment when RPOC does not resolve spontaneously, highly vascular tissue can lead to severe bleeding during the procedure. This study assessed clinical outcomes, procedural safety, and reproductive performance in patients with highly vascular RPOC treated with uterine artery embolization (UAE) prior to hysteroscopy, compared to those treated with hysteroscopy alone. Methods: This retrospective study included 42 women diagnosed with RPOC at University Medical Centre Ljubljana, Slovenia (2010-2020). Patients were divided into two groups: UAE followed by hysteroscopic resection (UAE + HSC, n = 21) and hysteroscopic resection alone (HSC-only, n = 21). Data on clinical outcomes, complications, and reproductive history were analyzed using Fisher's exact and t-tests (p < 0.05). Results: Groups were similar in baseline characteristics, except for greater vascularity in the UAE + HSC group (100% vs. 4.8%, p < 0.05). Bleeding >300 mL occurred more often in the UAE + HSC group, but all cases were managed conservatively and only one patient required transfusion. No uterine perforations occurred. Residual RPOC was found in one patient per group. Rates of endometritis, menstrual changes, and pelvic pain were comparable. Among those who attempted conception, live birth and miscarriage rates did not differ significantly. Conclusions: UAE prior to hysteroscopic surgery appears to be a safe and effective option for highly vascular RPOC, especially in patients at risk of hemorrhage, with no adverse impact on fertility. Further prospective studies are recommended. fertility high vascularity hysteroscopy reproductive outcomes retained products of conception uterine artery embolization plodnost visoka prekrvavljenost histeroskopija reproduktivni izidi zadržani produkti spočetja embolizacija maternične arterije true false true Angleški jezik Slovenski jezik Neznano 2026-05-05 11:55:04 2026-05-05 11:55:04 2026-05-06 03:51:48 0000-00-00 00:00:00 2025 0 0 Nasl. z nasl. zaslona; Opis vira z dne 14. 4. 2026; str. 1-10 iss. 22, [article no.] 8020 Vol. 14 Nov. 2025 0000-00-00 Zaloznikova Objavljeno NiDoloceno 0000-00-00 0000-00-00 0000-00-00 618.1 2077-0383 10.3390/jcm14228020 275156995 RAZ_Skuk_Eva_2025.pdf RAZ_Skuk_Eva_2025.pdf 1 44E029619EAAD22E9CBEED33D617E18A aea3ca7412e056e08c9133751e86fe5abe41e30e87e6c213caa82ce2979b96db a6c62382-4868-11f1-969d-001a4af901a5 https://dirros.openscience.si/Dokument.php?lang=slv&id=43796 https://www.mdpi.com/2077-0383/14/22/8020 1 7e09a2a6-4868-11f1-969d-001a4af901a5 https://dirros.openscience.si/Dokument.php?lang=slv&id=43795 Univerzitetni klinični center Ljubljana 0 0 0