20.500.12556/DiRROS-28942 Oral health-related quality of life after allogeneic bone marrow transplant a cross-sectional study Objectives: The aim of this study was to evaluate the oral health-related quality of life of patients with chronic graft-versus-host disease. Methods: A total of 22 patients with graft-versus-host disease aged 45.05 ± 14.66 years were enrolled in a single-centre cross-sectional study. Data from questionnaires on general health and diet, clinical examinations, and salivary tests were used to assess caries risks using the Cariogram computer programme. The Slovenian version of the Oral Health Impact Profile Questionnaire (OHIPSVN) was used to determine the oral health-related quality of life. Results: Compared to healthy individuals, patients with chronic graft-versus-host disease had a lower oral healthrelated quality of life and a lower stimulated salivary flow rate (in both cases p < 0.001). The OHIP summary score correlated with stimulated salivary pH (R = 0.4916, p = 0.0277) and caries risk (R = 0.5420, p = 0.0111). Conclusions: In conclusion, our results confirm that cGVHD has a negative impact on oral health-related quality of life due to lower stimulated salivary pH and elevated caries risk (reduced salivary pH, flow rate, buffering capacity, and elevated Streptococcus mutans and Lactobacillus bacteria count). These findings emphasise the importance of a comprehensive assessment of oral health and preventive care in patients with cGVHD and suggest that the integration of clinical and quality of life measures could lead to improved patient care strategies. dental caries oral health quality of life zobna gniloba ustno zdravje kakovost življenja true false true Angleški jezik Slovenski jezik Neznano 2026-04-14 12:28:01 2026-04-14 12:28:01 2026-04-15 03:57:38 0000-00-00 00:00:00 2025 0 0 Nasl. z nasl. zaslona; Opis vira z dne 10. 3. 2025; str. 1-14 iss. 5, [Article no.] 561 Vol. 13 2025 0000-00-00 Zaloznikova Objavljeno NiDoloceno 0000-00-00 0000-00-00 0000-00-00 616.31 2227-9032 10.3390/healthcare13050561 228414467 RAZ_Vovk_Nina_2025.pdf RAZ_Vovk_Nina_2025.pdf 1 BFB85B3F4C385AD45976BF6ACFA88FF9 d81ea715b1e316b06caf1ab5dba7ac81f564fde3a6837f66bb4205e09db66099 b692a811-37ec-11f1-9cc3-001a4af901a5 https://dirros.openscience.si/Dokument.php?lang=slv&id=43168 https://www.mdpi.com/2227-9032/13/5/561 1 a0146902-37ec-11f1-9cc3-001a4af901a5 https://dirros.openscience.si/Dokument.php?lang=slv&id=43167 Univerzitetni klinični center Ljubljana 0 0 0