20.500.12556/DiRROS-28907 The usefulness of a body shape index in assessing muscle function and strength in older adults hemodialysis patients Objective: This study investigates the relationship between a new anthropometric measure, the Body Shape Index (ABSI), and body composition and biochemical parameters in hemodialysis patients and, for the first time, the correlation between ABSI and muscle strength and function in these patients. Methods: A cross-sectional study was conducted on a sample of 80 patients who were regularly treated in the hemodialysis unit of a single medical center of the University Hospital of Ljubljana, Slovenia. General anthropometric parameters body mass index (BMI) and ABSI=(WC/(BMI2/3x height½) as well as body composition data (fat mass FM, fat-free mass FFM, fat-free mass index FFMI, skeletal muscle index SMI) were determined in 25 women (aged 74.5 ± 7.5 years) and 55 men (aged 70.1 ± 6.6 years) with overweight (25 kg/m2 ≤ BMI < 30 kg/m2) and obesity (BMI ≥ 30 kg/m2) by bioelectrical impedance analysis (BIA). Muscle strength was determined using a hand grip strength test, while muscle performance was assessed using the sit-to-stand test. Results: ABSI was significantly negatively associated with muscle strength, functional tests and SMI only in men. Based on the median ABSI value (0.090273 m11/6·kg−2/3 in women and 0.090893 m11/6·kg−2/3 in men), women with a higher ABSI had a significantly higher glucose concentration than those with a lower ABSI. Men with a lower ABSI obtained significantly better results in the hand grip test, sit-to-stand test and waist circumference (WC). In conclusion, our findings suggest an inverse association between ABSI and muscle strength and function in male hemodialysis patients, indicating that higher ABSI may reflect poorer physical condition in this population. Further longitudinal studies are needed to explore the clinical significance of this relationship. Cilj: Namen te raziskave je preučiti razmerje med novo antropometrično mero, indeksom oblike telesa (ABSI), ter sestavo telesa in biokemičnimi parametri pri bolnikih na hemodializi ter – prvič – povezavo med ABSI ter mišično močjo in funkcijo pri teh bolnikih. Metode: Izvedena je bila presečna študija na vzorcu 80 bolnikov, ki so bili redno zdravljeni v enoti za hemodializo Univerzitetnega kliničnega centra Ljubljana, Slovenija. Splošni antropometrični parametri, indeks telesne mase (ITM) in ABSI = (obseg pasu / (ITM²/³ × višina¹/²)), ter podatki o telesni sestavi (maščobna masa – FM, brezmaščobna masa – FFM, indeks brezmaščobne mase – FFMI, indeks skeletne mišične mase – SMI) so bili določeni pri 25 ženskah (povprečna starost 74,5 ± 7,5 let) in 55 moških (povprečna starost 70,1 ± 6,6 let) s prekomerno telesno težo (25 kg/m² ≤ ITM < 30 kg/m²) in debelostjo (ITM ≥ 30 kg/m²) z uporabo bioelektrične impedančne analize (BIA). Mišična moč je bila ocenjena s testom stiska roke, mišična zmogljivost pa s testom vstajanja s stola. Rezultati: ABSI je bil statistično značilno negativno povezan z mišično močjo, funkcionalnimi testi in SMI le pri moških. Glede na mediane vrednosti ABSI (0,090273 m¹¹/⁶·kg⁻²/³ pri ženskah in 0,090893 m¹¹/⁶·kg⁻²/³ pri moških) so imele ženske z višjim ABSI statistično značilno višjo koncentracijo glukoze kot tiste z nižjim ABSI. Moški z nižjim ABSI so dosegli statistično značilno boljše rezultate pri testu stiska roke, testu vstajanja s stola in imeli manjši obseg pasu. Zaključek: Naši rezultati kažejo na obratno povezavo med ABSI ter mišično močjo in funkcijo pri moških bolnikih na hemodializi, kar nakazuje, da bi lahko višji ABSI odražal slabše telesno stanje pri tej populaciji. Za razumevanje kliničnega pomena te povezave bodo potrebne nadaljnje longitudinalne raziskave. hemodialysis muscle strenght sarcopenia hemodializa mišična moč sarkopenia true false true Angleški jezik Slovenski jezik Neznano 2026-04-13 13:49:14 2026-04-13 13:49:15 2026-04-14 03:50:24 0000-00-00 00:00:00 2025 0 0 Nasl. z nasl. zaslona; Opis vira z dne 10. 11. 2025; Št. članka: 1585193; str. 1-11 [article no.] 1585193 Vol. 16 3. nov 2025 0000-00-00 Zaloznikova Objavljeno NiDoloceno 0000-00-00 0000-00-00 0000-00-00 616.74-007.23 1664-2392 10.3389/fendo.2025.1585193 256467971 RAZ_Knap_Bojan_2025.pdf RAZ_Knap_Bojan_2025.pdf 1 9325FDC7838A6E3358BB65609949D9FE 4f379e1fc74e9e00e4552c17a1bcce8439e447cbedf06282c2693975e25ad210 fbdf43c0-372e-11f1-9cc3-001a4af901a5 https://dirros.openscience.si/Dokument.php?lang=slv&id=43109 https://www.frontiersin.org/journals/endocrinology/articles/10.3389/fendo.2025.1585193/full 1 cdf2fc49-372e-11f1-9cc3-001a4af901a5 https://dirros.openscience.si/Dokument.php?lang=slv&id=43107 Univerzitetni klinični center Ljubljana 0 0 0