20.500.12556/DiRROS-28862 The significance of isolated de novo red patches in the bladder in patients referred with suspected urinary tract cancer results from the IDENTIFY study Objectives: To assess the contemporary malignancy rate in isolated de novo red patchesin the bladder and associated risk factors for better selection of red patch biopsy.Patients: Patients from the IDENTIFY dataset; Patients referred to secondary carewith suspected urinary tract cancer and found to have isolated de novo red patcheson cystoscopy.Methods: We reported the unadjusted cancer prevalence in isolated de novo redpatches that were biopsied; multivariable logistic regression was used to explorecancer-associated risk factors including age, sex, smoking, type of haematuria, LUTS,UTIs and a suspicious-looking red patch (as reported by the cystoscopist). Sub-analysis of these by clinical role and experience was performed.Results: A total of 1110 patients with isolated de novo red patches were included.41.5% (n = 461) were biopsied, with a malignancy rate of 12.8% (59/461), whichwas significantly higher in suspicious versus non-suspicious red patches (19.1%vs. 2.81%, p < 0.01). There was a significant association between bladder cancer andage (OR 1.04, 95% CI 1.01–1.07, p = 0.01), smoking history (OR 2.62, 95% CI 1.09–6.27, p = 0.03) and suspicious-looking patch (OR 6.50, 95% CI 2.47–17.1, p < 0.01).The majority of malignancies were in over 60-year-olds. Malignancy rates in suspicious versus non-suspicious red patches did not differ significantly betweenclinical roles or experiences.Limitations included subjectivity in classifying a suspicious patch and selection biasas not all patches were biopsied.Conclusions: Many patients still undergo unnecessary biopsies under general anaes-thetic for isolated de novo red patches. Clinicians should consider the patient’s age,smoking status and how suspicious-looking the patch is, before deciding on surveil-lance versus biopsy to improve cancer diagnostic yield. biopsy bladder cancer cystoscopy haematuria red patch risk factors true false true Angleški jezik Ni določen Neznano 2026-04-09 14:25:00 2026-04-09 14:25:00 2026-04-10 03:55:42 0000-00-00 00:00:00 2025 0 0 Nasl. z nasl. zaslona; Opis vira z dne 26. 2. 2026; str. 1-8 issue 1, [article no.] e475 Vol. 6 2025 0000-00-00 Zaloznikova Objavljeno NiDoloceno 0000-00-00 0000-00-00 0000-00-00 616-006 2688-4526 10.1002/bco2.475 269692419 RAZ_Khadhouri_Sinan_2025.pdf RAZ_Khadhouri_Sinan_2025.pdf 1 384BB39E33C6C85D203F441D2406EF0F 05722f996c7e88d61e2bd3e39e6f0e22aa00dd21a3465330b1afacf02a868d2b 485c48c9-340f-11f1-b941-001a4af901a5 https://dirros.openscience.si/Dokument.php?lang=slv&id=43019 Univerzitetni klinični center Ljubljana 0 0 0