20.500.12556/DiRROS-28832 Robot-assisted radical prostatectomy after Rezūm a case report and literature review Minimally invasive surgical therapies (MISTs), such as Rezum¯ ™ Water Vapor Therapy, are emerging treatment options for benign prostatic obstruction (BPO). When prostate cancer is subsequently diagnosed, radical prostatectomy may still be indicated. However, evidence regarding intraoperative challenges and the surgical and functional outcomes of robot-assisted radical prostatectomy (RARP) following Rezum remains limited. We ¯ report the first documented case of RARP following Rezum in a 68-year-old man. He ¯ initially underwent Rezum for symptomatic BPO. Due to rising PSA, a suspicious lesion on ¯ MRI, and a biopsy-confirmed high-risk prostate carcinoma, radical surgery was performed. Intraoperatively, dense fibrosis and altered tissue planes required precise dissection and a level 2 bilateral nerve-sparing approach. A systematic review revealed no previously published cases of RARP after Rezum. On the other hand, RARP after transurethral ¯ resection of the prostate (TURP) is associated with increased operative time, blood loss, and bladder neck reconstruction, though late continence and biochemical recurrence rates are similar to those in treatment-naïve patients. In conclusion, RARP after ablative BPO therapies is feasible but may present unique technical challenges. Larger prospective studies are needed to develop standardized management strategies. prostate cancer robotic surgery robot-assisted radical prostatectomy RARP Rezum benign prostatic obstruction BPO intraoperative fibrosis minimally invasive surgical therapies MISTs true false true Angleški jezik Ni določen Neznano 2026-04-08 15:29:13 2026-04-08 15:29:13 2026-04-09 03:51:24 0000-00-00 00:00:00 2026 0 0 Nasl. z nasl. zaslona; Opis vira z dne 26. 2. 2026; str. 1-7 issue 2, [article no.] 362 Vol. 16 2026 0000-00-00 Zaloznikova Objavljeno NiDoloceno 0000-00-00 0000-00-00 0000-00-00 616-089:616-006 2075-1729 10.3390/life16020362 269687043 RAZ_Cerovic_Kosta_2026.pdf RAZ_Cerovic_Kosta_2026.pdf 1 9A4E7871DF86A3E339B831E209336B79 39a364c1bb3ded709b64f0c882183ce47c18681b30b41c8975bdc7f05fac9a3b 0452a35a-334f-11f1-b941-001a4af901a5 https://dirros.openscience.si/Dokument.php?lang=slv&id=42964 Univerzitetni klinični center Ljubljana 0 0 0