20.500.12556/DiRROS-28736 Electrosurgical devices in gynecologic oncology a systematic review of clinical studies Introduction: Electrosurgical instruments are a crucial component in the surgical treatment of gynecologic malignancies, enabling precise dissection and effective hemostasis, influencing blood loss, operative time and complication rates. Considering their importance in oncological outcomes and increasing variety, comparative data in the literature remains limited. Our aim is to comprehensively assess and compare clinical outcomes across electrosurgical modalities in gynecologic cancer surgery. Methods: Following PRISMA guidelines, we performed a systematic search of three electronic databases (PubMed, Cochrane Library, Scopus). Eligible studies since 2005 enrolled women (≥18 years) undergoing surgery for gynecological neoplasms, in which electrosurgical devices were used. Clinically relevant outcomes, such as intraoperative blood loss, operative time, perioperative complication rates, surgeon’s experience and length of hospital stay were compared. Results: 359 publications were reviewed after literature search, 10 of them fitted the inclusion criteria, 1 additional publication was added after references review. Most of the studies (36.4%) evaluated cervical cancer only, followed by studies that included both cervical and endometrial cancer (27.3%), while 18.2% of the studies focused on endometrial and ovarian cancer each. Majority of the articles (82%) evaluated advanced electrosurgical devices alone or in comparison with standard electrosurgery or conventional methods. LigaSure was the most commonly used advanced electrosurgical device, followed by THUNDERBEAT, PlasmaJetTM, PlasmaKinetic tissue management system and ERBE BiClamp® forceps. All of the studies assessed more than one perioperative outcome, with the most common being estimated blood loss, operative time and duration of hospitalization. Discussion: Despite heterogeneous design and outcomes, most findings suggest that advanced electrosurgical devices are associated with mostly better perioperative outcomes in oncological patients undergoing surgery. It can be concluded that the effectiveness of the device and the appropriate instrument selection differs between malignancies, depending on the cancer type and operative procedure performed. Given the diversity of the studies we believe that additional well-designed studies using standardized outcomes sets are needed. advanced bipolar vessel sealing electrosurgical devices gynecological cancer surgical outcomes systematic review true false true Angleški jezik Ni določen Neznano 2026-03-31 13:03:48 2026-03-31 13:03:48 2026-04-01 03:58:42 0000-00-00 00:00:00 2026 0 0 Nasl. z nasl. zaslona; Opis vira z dne 23. 3. 2026; str. 1-11 [article no.] 1772803 Vol. 13 2026 0000-00-00 Zaloznikova Objavljeno NiDoloceno 0000-00-00 0000-00-00 0000-00-00 618.1 2296-875X 10.3389/fsurg.2026.1772803 272721155 RAZ_Lazhovska_Ekaterina_2026.pdf RAZ_Lazhovska_Ekaterina_2026.pdf 1 D1B35C99EFAE3BD5D5F4876E356C560A afe982fe801ee36383883019f270982647799fab67b9893892ac318c55f79ade 78dd5c80-2cf1-11f1-9147-001a4af901a5 https://dirros.openscience.si/Dokument.php?lang=slv&id=42758 https://www.frontiersin.org/journals/surgery/articles/10.3389/fsurg.2026.1772803/full 1 4bd2ea0e-2cf1-11f1-9147-001a4af901a5 https://dirros.openscience.si/Dokument.php?lang=slv&id=42757 Univerzitetni klinični center Ljubljana 0 0 0