20.500.12556/DiRROS-27874 Contrast-enhanced ultrasound (CEUS) and ultra-microangiography (UMA) in critically ill children with acute kidney injury Acute kidney injury (AKI) is an acute condition of impaired kidney function with decreased glomerular filtration rate, which results in dysregulation in volume, electrolyte, and acid–base equilibrium. AKI can be a life-threatening condition and can also lead to chronic kidney disease. It is important to diagnose AKI early in the course of the disease or to predict its development, as this can influence therapeutic decisions, outcome, and, consequently, the prognosis. In clinical practice, an elevated serum creatinine concentration remains the most common laboratory indicator for diagnosing AKI. However, due to the delay in its rise, creatinine levels are often insensitive and inaccurate for early diagnosis. Novel biomarkers of kidney tubular injury and the renal angina index have shown promise in predicting AKI earlier and more accurately. Contrast-enhanced ultrasonography (CEUS) and ultra-microangiography (UMA) are radiological methods that can quantify renal microperfusion and may be able to predict the development of AKI. They have not yet been used for quantifying renal perfusion in children with risk factors for developing AKI. Further research is needed to compare these sonographic techniques with the renal angina index and emerging kidney injury biomarkers for predicting acute kidney injury (AKI) in both children and adults acute kidney injury contrast-enhanced ultrasound ultra-microangiography true false true Angleški jezik Ni določen Neznano 2026-02-26 13:37:19 2026-02-26 13:37:19 2026-02-27 03:58:42 0000-00-00 00:00:00 2024 0 0 Nasl. z nasl. zaslona; Opis vira z dne 24. 3. 2025; str. 1-11 iss. 10, ǂ[article no.] ǂ1205 Vol. 11 2024 0000-00-00 Zaloznikova Objavljeno NiDoloceno 0000-00-00 0000-00-00 0000-00-00 616-053.2 2227-9067 10.3390/children11101205 230016003 RAZ_Ogorevc_Nace_2024.pdf RAZ_Ogorevc_Nace_2024.pdf 1 0757EA5FA5C8C340148C6B341BA2A20D 39db4a7c49a944a2c5ae4a3729d62f86de4ff93b6cc52c155ab1e8db5eb42780 019c7ca7-1310-11f1-9cb0-001a4af901a5 https://dirros.openscience.si/Dokument.php?lang=slv&id=41019 https://www.mdpi.com/2227-9067/11/10/1205/pdf?version=1727691044 1 e4bb559e-130f-11f1-9cb0-001a4af901a5 https://dirros.openscience.si/Dokument.php?lang=slv&id=41018 Univerzitetni klinični center Ljubljana 0 0 0