20.500.12556/DiRROS-25481 Dve desetletji delovanja Oddelka za molekularno diagnostiko na Onkološkem inštitutu Ljubljana Two Decades of the Department of Molecular Diagnostics at the Institute of Oncology Ljubljana Oddelek za molekularno diagnostiko je bil na Onkološkem inštitutu Ljubljana ustanovljen leta 2005 na pobudo znan. svet., dr. Srdjana Novakovića. V 20-letnem obdobju je Oddelek za molekularno diagnostiko postal osrednji laboratorij v Sloveniji tako za genetsko testiranje posameznikov z večjo ogroženostjo za dedne oblike raka kakor tudi za molekularno-genetsko te-stiranje različnih vrst solidnih tumorjev, kjer je informacija o genotipu tumorja pomembna pri načrtovanju zdravljenja, pomoč pri diagnozi ali prognozi bolezni. Posebno področje dela oddelka predstavljajo farmakogenetske preiskave, s katerimi ocenimo napoved presnavljanja zdravil ter opredelimo bolnike z večjim tveganjem za hude neželene učinke. Oddelek za molekularno diagnostiko se lahko po zahtevnosti in kakovosti svojih preiskav primerja z mednarodno priznanimi centri na področju molekular-ne diagnostike. To potrjuje z obsežnim naborom preiskav, ki sledijo priporočilom mednarodnih strokovnih smernic za obravnavo onkoloških bolnikov, ter z rednim sodelovanjem in uspešno opra-vljenimi zunanjimi kontrolami kakovosti. Slovenskim onkološkim bolnikom je s tem omogočen dostop do celovitih molekularno--genetskih preiskav znotraj države, brez potrebe po napotitvah v tujino. Pomemben mejnik predstavlja tudi dogovor z Zavodom za zdravstveno zavarovanje Slovenije o financiranju teh storitev, kar bolnikom zagotavlja dostopno in visokokakovostno diagnostiko ter bolniku prilagojeno zdravljenje s tarčnimi zdravili v skladu z najso-dobnejšimi mednarodnimi smernicami in brez dodatnih stroškov za bolnike. Na molekularno-genetsko testiranje na Oddelek za molekularno diagnostiko lahko svoje bolnike napotujejo zdravniki iz različnih zdravstvenih ustanov iz celotne Slovenije. The Department of Molecular Diagnostics at the Institute of Oncology Ljubljana was established in 2005 at the initiative of Prof. Dr. Srdjan Novaković. Over the past 20 years, it has evolved into the central national laboratory for genetic testing of individuals with a higher risk of hereditary cancer syndromes, as well as for molecular genetic testing of various types of solid tumours, where tumour genotyping plays a key role in diagnosis, treatment planning, and prognosis. A special area of the department’s work involves pharma-cogenetic testing, which identifies patients at increased risk of severe adverse drug effects. In terms of the complexity and quality of its diagnostic services, the Department of Molecular Diagnostics is com-parable to internationally recognized centres performing molecular diagnostics. This is demonstrated by its extensive range of tests that follow international clinical guidelines for the management of cancer patients, as well as by its regular participation and successful perfor-mance in external quality assessment schemes. As a result, Slovenian cancer patients have access to comprehensive molecular genetic testing within the country, without the need for referral abroad. An important step forward has also been the agreement with the Health Insurance Institute of Slovenia (ZZZS) on the funding of these services, ensuring patients have access to high-quality diagnostics and personalized treatment with targeted therapies, in accordance with the most up-to-date international guidelines and without any additional costs to patients. Patients from healthcare institutions across Slovenia may be referred for molecular genetic testing to the Department of Molecular Diagnostics. molekularna diagnostika onkološka diagnostika molekularna testiranja true false true Onkološki inštitut Ljubljana Ljubljana Slovenski jezik Angleški jezik by Authors Neznano 2026-01-21 13:07:43 2026-01-21 13:07:43 2026-01-23 03:53:26 0000-00-00 00:00:00 2025 0 Ljubljana 0 str. 52-60 št. 2 Letn. 29 dec. 2025 0000-00-00 Zaloznikova Objavljeno NiDoloceno 0000-00-00 0000-00-00 2025-12-01 616-07 1408-1741 10.25670/oi2025-013on 262936323 RAZ_Skerl_Petra_2025.pdf RAZ_Skerl_Petra_2025.pdf 1 3F65273BE64B917D81145C30135F0CB2 3d79c02591cb009c70e156c417b11c4e35c6af2624f1dc1050d562b75174e3cb 3ae6b07c-f6c2-11f0-a15d-001a4af901a5 https://dirros.openscience.si/Dokument.php?lang=slv&id=38620 Onkološki inštitut Ljubljana Onkologija : strokovni časopis za zdravnike 0 0 0