20.500.12556/DiRROS-25425 Lost and not found randomized controlled trial of cognitive behavioural therapy for weight-loss in patients with chronic kidney disease Introduction: Managing obesity in patients with chronic kidney disease is crucial for managing disease progression. Psychological interventions, particularly cognitive behavioral therapy, can support lifestyle changes. This study aimed to evaluate the efficacy of a cognitive behavioral therapy intervention for obesity management in patients with chronic kidney disease. Methods: Forty patients with chronic kidney disease (stages 2–4) were randomized to either an intervention group (nutritional and physical activity counseling and 16-week cognitive behavioral therapy) or a control group (nutritional and physical activity counseling only). Primary outcomes were body mass index (BMI) and proteinuria. Results: The intervention group lost an average of 5.42 kg (BMI decrease: 1.82 kg/m²), compared to 1.53 kg (BMI decrease: 0.53 kg/m²) in the control group. A significant group-by-time interaction was observed for BMI (F(1,36) = 32.24, p = 0.004, ŋ²=0.21), favoring the intervention group. Effects remained significant at three-month follow-up, with an average weight loss of 4.63 kg (BMI decrease: 1.59 kg/m²) in the intervention group and 2.51 kg (BMI decrease: 0.87 kg/m²) in control group (F(2,70) = 5.54, p = 0.026, ŋ²=0.12). Changes in proteinuria did not differ between groups. Conclusion: Cognitive behavioral therapy was effective and well-tolerated for promoting weight loss with most of the lost weight maintained at the three-month follow-up. This intervention may offer a valuable non-pharmacological treatment option for weight management in patients with chronic kidney disease. sport chronic kidney disease cognitive behavioral therapy obesity weight management improve patient well-being weight-loss šport konference kronična ledvična bolezen izboljšanje bolnikovega počutja vadba hujšanje true false true Angleški jezik Slovenski jezik Neznano 2026-01-20 11:42:48 2026-01-20 11:42:49 2026-01-21 03:50:01 0000-00-00 00:00:00 2025 0 0 Nasl. z nasl. zaslona; Opis vira z dne 23. 6. 2025; str. 594–604 issue 4 Vol. 48 2025 0000-00-00 PostprintKoncna Objavljeno NiDoloceno 0000-00-00 0000-00-00 0000-00-00 796.01:616.61-008.6 0160-7715 10.1007/s10865-025-00583-w 240312835 RAZ_Kurnik_Mesaric_Katja_2025.pdf RAZ_Kurnik_Mesaric_Katja_2025.pdf 1 4269BFC583D9290DFE127F6CCD29920E a8ee332045f17dd92379fcf41e1ae7b101d4ada5009e31a6875eca72f1941126 f04639bb-f5ec-11f0-a15d-001a4af901a5 https://dirros.openscience.si/Dokument.php?lang=slv&id=38511 https://link.springer.com/article/10.1007/s10865-025-00583-w 1 c50d36e0-f5ec-11f0-a15d-001a4af901a5 https://dirros.openscience.si/Dokument.php?lang=slv&id=38510 Univerzitetni klinični center Ljubljana 0 0 0