20.500.12556/DiRROS-25151 Impact of spaceflight on endocrine, metabolic and kidney function: current evidence, open issues, and potential countermeasures Changes in endocrine and kidney functions have been associated with spaceflight. Here, we discuss the most relevant evidence about the impact of spaceflight on the cardiometabolic system, the cardiorenal function and the reproductive/gonadal axis. Notably, these changes appear to be interrelated with other organ/system functions, suggesting the need of a systemic approach leading to a more comprehensive understanding of physiological and health-related impacts of the space environment. Therefore, this review will also focus on the need to move space endocrinological research to multi-omics approaches and the implementation of “machine learning” and “data mining” strategies. cardiorenal function metabolic changes microgravity oxidative stress reproduction space exposome. a ledvice delovanje kardiorenalna funkcija presnovne spremembe mikrogravitacija true false true Angleški jezik Slovenski jezik © The Author(s) Neznano 2026-01-12 16:01:14 2026-01-12 16:01:14 2026-01-13 03:45:19 0000-00-00 00:00:00 2025 0 0 Nasl. z nasl. zaslona; Soavtorji: Giulia Ricci, Marco Narici, Francesca Ferranti; Opis vira z dne 12. 1. 2026; str. 1-8 art. 365 Vol. 23 2025 0000-00-00 Zaloznikova NiDoloceno NiDoloceno 0000-00-00 2025-11-13 2025-12-29 611.61:612 1741-7007 10.1186/s12915-025-02471-w 264401667 2026_01_12_102_NariciM_264401667.pdf 2026_01_12_102_NariciM_264401667.pdf 1 98C4A0AF58523538FA34F762BA91ABBB 8c22e03598a468bdb07fe7dda65bee2432b4b0127ae4520c885be8dc67f8a5e8 fb4d3251-efc7-11f0-94a7-001a4af901a5 https://dirros.openscience.si/Dokument.php?lang=slv&id=37896 https://pmc.ncbi.nlm.nih.gov/articles/PMC12752379/ 1 8b981ab7-efc7-11f0-94a7-001a4af901a5 https://dirros.openscience.si/Dokument.php?lang=slv&id=37895 Znanstveno-raziskovalno središče Koper / Centro di Ricerche Scientifiche Capodistria 0 0 0