20.500.12556/DiRROS-24953 Influence of hypnosis and acupuncture on perioperative complications Background: This randomised, single-centre study and original research manuscript aimed to evaluate whether perioperative hypnosis and acupuncture can reduce postoperative nausea and vomiting (PONV), opioid use, and other complications in spinal surgery compared to standard pharmacological management. Methods: In total, 60 patients undergoing spinal surgery were divided into three groups regarding antiemetic prevention: Hypnosis and acupuncture (HG), hypnosis, acupuncture, and antiemetic (HAG), and standard control with antiemetic (CG). Hypnosis was performed one day before surgery, or patients received premedication with midazolam on the day of surgery. Anaesthesia was induced and maintained with propofol and remifentanil. Acupuncture was performed bilaterally at points LI4 and PC6 after induction of anaesthesia. Postoperatively, the consumption of opioids and antiemetics, satisfaction and well-being, length of stay and complications were recorded. Results: In all groups, additional opioids were administered in the first hour after surgery (p = 0.4). In the ICU, only one patient in the HAG and two patients in the CG and HG required additional analgesics (p = 0.8). Overall satisfaction (9/9/0 vs. 10/6/4 vs. 9/7/3; p = 0.4) and well-being scores (10/8/0 vs. 13/5/2 vs. 13/5/1; p = 0.5) were high across all groups, with no significant differences. Two patients in CG experienced mild complications. The length of hospitalisation was similar (3 days in CG vs. 4 days in HAG and HG (p = 0.7). Only one patient in the HG required antiemetics; none were needed in CG or HAG (p = 0.4). Conclusions: Within the constraints of this exploratory single-centre trial, hypnosis appeared to provide anxiolytic benefits comparable to benzodiazepines, and intraoperative acupuncture did not increase PONV despite reduced pharmacological prophylaxis. No significant differences were detected in opioid and antiemetic consumption. Larger, adequately powered studies are needed to confirm these findings and optimise the timing and modality of non-pharmacological interventions. spinal surgery anaesthesia antiemetic acupuncture hypnosis operacije hrbtenice anestezija antiemetiki akupunktura hipnoza true false true Angleški jezik Slovenski jezik Neznano 2026-01-05 14:30:36 2026-01-05 14:30:37 2026-01-06 03:43:51 0000-00-00 00:00:00 2025 0 0 Nasl. z nasl. zaslona; Opis vira z dne 24. 11. 2025; str. 1-12 iss. 22, [article no.] 2992 Vol. 13 2025 0000-00-00 Zaloznikova Objavljeno NiDoloceno 0000-00-00 0000-00-00 0000-00-00 616-089 2227-9032 10.3390/healthcare13222992 258344451 RAZ_Markovic_Bozic_Jasmina_2025.pdf RAZ_Markovic_Bozic_Jasmina_2025.pdf 1 2141C5DA3264768738C897286864423C 0e5cb927b43f29d8f0a7f9fc47203555c9b686135c0da3334faa4035c8808d8d e4fc538f-ea3a-11f0-94a7-001a4af901a5 https://dirros.openscience.si/Dokument.php?lang=slv&id=37383 https://www.mdpi.com/2227-9032/13/22/2992 0 b9c33a20-ea3a-11f0-94a7-001a4af901a5 https://dirros.openscience.si/Dokument.php?lang=slv&id=37382 Univerzitetni klinični center Ljubljana 0 0 0