20.500.12556/DiRROS-24877 Association of preoperative smoking with the occurrence of postoperative pulmonary complications a post hoc analysis of an observational study in 29 countries Introduction: While smoking has been consistently identified as a significant contributor to postoperative complications, the existing literature on its association with postoperative pulmonary complications remains conflicting. Aim: We examined the association of preoperative smoking with the occurrence of postoperative pulmonary complications (PPCs). Methods: Post hoc analysis of an observational study in 146 hospitals across 29 countries. We included patients at increased risk of PPCs, according to the Assess Respiratory Risk in Surgical Patients in Catalonia (ARISCAT) score (≥ 26 points). The primary endpoint was the occurrence of one or more predefined PPCs in the first five postoperative days, including unplanned postoperative need for supplementary oxygen, respiratory failure, unplanned need for invasive ventilation, ARDS, pneumonia and pneumothorax. Secondary endpoints included length of hospital stay and in–hospital mortality. We performed propensity score matching to correct for factors with a known association with postoperative outcomes. Results: Out of 2632 patients, 531 (20.2 %) patients were smokers and 2102 (79.8 %) non-smokers. At five days after surgery, 101 (19.0 %) smokers versus 404 (19.2) non–smokers had developed one or more PPCs (P = 0.95). Respiratory failure was more common in smokers (5.1 %) than non–smokers (3.0 %) (P = 0.02), while rates of other PPCs like need for supplementary oxygen, invasive ventilation, ARDS, pneumonia, or pneumothorax did not differ between the groups. Length of hospital stay and mortality was not different between groups. Propensity score matching did not change the findings. Conclusion: The occurrence of PPCs in smokers is not different from non–smokers. anaesthesia intraoperative ventilation smoking postoperative outcome postoperative pulmonary complications PPCs respiratory complications true false true Angleški jezik Ni določen Neznano 2025-12-23 11:00:56 2025-12-23 11:00:56 2025-12-24 04:01:12 0000-00-00 00:00:00 2025 0 0 Nasl. z nasl. zaslona; Opis vira z dne 23. 9. 2025; str. 1-10 Vol. 104, [article no.] 111856 2025 0000-00-00 Zaloznikova Objavljeno NiDoloceno 0000-00-00 0000-00-00 0000-00-00 617 1873-4529 10.1016/j.jclinane.2025.111856 249939459 RAZ_Dorland_Galina_2025.pdf RAZ_Dorland_Galina_2025.pdf 1 158808A9AFFC6BA152FEFE039F941916 c3200d74552efa17b61580ae703baecc1bcda1a3b02c59c8821554f5b6c07ae0 802206d4-dfe6-11f0-94a7-001a4af901a5 https://dirros.openscience.si/Dokument.php?lang=slv&id=37225 https://www.sciencedirect.com/science/article/pii/S0952818025001163 0 8b1fd9d9-dfe6-11f0-94a7-001a4af901a5 https://dirros.openscience.si/Dokument.php?lang=slv&id=37226 Univerzitetni klinični center Ljubljana 0 0 0