20.500.12556/DiRROS-24745 Emerging trends and recent progress of MXene as a promising 2D material for point of care (POC) diagnostics Two-dimensional (2D) nanomaterials with chemical and structural diversity have piqued the interest of the scientific community due to their superior photonic, mechanical, electrical, magnetic, and catalytic capabilities that distinguish them from their bulk counterparts. Among these 2D materials, two-dimensional (2D) transition metal carbides, carbonitrides, and nitrides with a general chemical formula of Mn+1XnTx (where n = 1–3), together known as MXenes, have gained tremendous popularity and demonstrated competitive performance in biosensing applications. In this review, we focus on the cutting-edge advances in MXene-related biomaterials, with a systematic summary on their design, synthesis, surface engineering approaches, unique properties, and biological properties. We particularly emphasize the property–activity–effect relationship of MXenes at the nano– bio interface. We also discuss the recent trends in the application of MXenes in accelerating the performance of conventional point of care (POC) devices towards more practical approaches as the next generation of POC tools. Finally, we explore in depth the existing problems, challenges, and potential for future improvement of MXene-based materials for POC testing, with the goal of facilitating their early realization of biological applications. MXenes 2D nanomaterials biosensors POC testing MXeni 2D-nanomateriali biosenzorji POC-testiranje testiranje ob bolniku true false true MDPI Švica Angleški jezik Slovenski jezik © 2023 by the authors. Neznano 2025-12-16 13:31:56 2025-12-16 13:31:56 2025-12-17 03:58:04 0000-00-00 00:00:00 2023 0 0 Nasl. z nasl. zaslona; Opis vira z dne 17. 2. 2023; str. 1-24 iss. 4, [article no.] 697 Vol. 13 Feb. 2023 0000-00-00 Zaloznikova Objavljeno NiDoloceno 2023-01-09 2023-02-08 2023-02-12 620.1/.2 2075-4418 10.3390/diagnostics13040697 142071043 https://www.mdpi.com/2075-4418/13/4/697 1 38f62103-da7b-11f0-94a7-001a4af901a5 https://dirros.openscience.si/Dokument.php?lang=slv&id=36980 RAZ_Chouhan_Raghuraj_S._2023.pdf RAZ_Chouhan_Raghuraj_S._2023.pdf 1 91BCB1DBA2E331655D51C1F70D052285 1126646d1a0a641953193a071b6306916d39d20779d41476bcc842a212bfec02 b39d3ece-da7b-11f0-94a7-001a4af901a5 https://dirros.openscience.si/Dokument.php?lang=slv&id=36981 Institut Jožef Stefan 0 0 0