20.500.12556/DiRROS-24716 Recent progress and advancement in detecting Methylmercury using a battery of biosensors and biomolecular-based techniques An updated overview Methylmercury (MeHg) represents the most toxic form of mercury, owing to its ability to permeate both the blood-brain and placental barriers, leading to bioaccumulation in organisms. In the marine food web, MeHg concentrations can reach levels millions of times higher than those found in the surrounding environment, posing significant ecological and human health risks. This review provides a comprehensive overviews and critical evaluation of the available biosensor detection platforms for the detection of MeHg, with a focus on their performance based on key parameters such as (i) sensitivity, (ii) selectivity, (iii) response time, and (iv) adaptability to diverse environmental matrices. We examine recent advancements in MeHg biosensing technologies, emphasizing innovative approaches that surpass current methodologies regarding detection limits, reversibility, response time, and operational stability. Furthermore, we present an in-depth discussion on future directions for the development of in situ MeHg detection platforms, with potential applications in both biomedical and environmental monitoring. The review concludes by outlining the challenges and opportunities for advancing MeHg sensing technologies to enhance real-time detection in aqueous environments. kemija okolja biosenzorji nanodelci true false true Elsevier Nizozemska Angleški jezik Slovenski jezik © 2025 The Authors. Neznano 2025-12-15 12:18:00 2025-12-15 12:18:00 2025-12-16 03:44:29 0000-00-00 00:00:00 2025 0 0 str. 1-21 Art. 118157 Vol. 184 2025 0000-00-00 Zaloznikova Objavljeno NiDoloceno 2024-07-03 2025-01-20 2025-01-21 543 0165-9936 10.1016/j.trac.2025.118157 224039171 RAZ_Mabes_Raj_Allwin_2025.pdf RAZ_Mabes_Raj_Allwin_2025.pdf 1 4B6AD678DDD1310EB64BA084E032342F 50e953903b0370de0a30dd52d7074c11cbcf389f647e8a285c75ae33e8f4c645 1f9b86e0-d9a8-11f0-94a7-001a4af901a5 https://dirros.openscience.si/Dokument.php?lang=slv&id=36916 Institut Jožef Stefan 0 0 0