20.500.12556/DiRROS-24568 Electrochemotherapy (ECT) in treatment of mucosal head and neck tumors an international network for sharing practices on ECT (InspECT) study group report The aim of this multicenter study was to evaluate the effectiveness and safety of electrochemotherapy (ECT) for the treatment of mucosal tumors in the head and neck. A total of 71 patients with 84 nodules of different histologies in the oral cavity, pharynx and larynx treated by ECT were evaluated. The data were collected from the InspECT database from 10 participating centers throughout Europe. Primary and recurrent/secondary tumors of different histologies were treated. The overall response rate was 65 %, with a 33 % complete response rate with limited side effects. The response rates of the primary and secondary tumors were not different. However, smaller tumors responded better than tumors larger than 3 cm in diameter. Furthermore, the tumors that were treated with curative intent responded significantly better than those treated with palliative intent. This study demonstrated the feasibility, safety and effectiveness of ECT in a larger cohort of patients with mucosal lesions in the head and neck region. Based on the available data, ECT can be used for the treatment of recurrent and, in some cases, primary mucosal tumors located in the oral cavity, larynx, and pharynx. A better response was obtained in patients with smaller primary tumors treated with curative intent. electrochemotherapy mucosal cancer head cancer neck cancer ECT true false true Angleški jezik Ni določen Neznano 2025-12-05 14:55:37 2025-12-05 14:55:37 2025-12-06 03:47:57 0000-00-00 00:00:00 2024 0 0 Nasl. z nasl. zaslona; Opis vira z dne 1. 12. 2024; str. 108473-1-108473-8 iss. 9 Vol. 50 Sept. 2024 0000-00-00 Zaloznikova Objavljeno apc 0000-00-00 0000-00-00 0000-00-00 616-006 1532-2157 10.1016/j.ejso.2024.108473 217141507 RAZ_Bertino_Giulia_2024.pdf RAZ_Bertino_Giulia_2024.pdf 1 A2472EAABF731C4A2C300104CA71F5C9 8bb65d7ae9dab8300ea8763e15cb415ff9ea3d22cd00e2f90434d2b42b4a8b5a 3a2bee89-d1e2-11f0-94a7-001a4af901a5 https://dirros.openscience.si/Dokument.php?lang=slv&id=36652 https://sciencedirect.com/science/article/pii/S0748798324005250 1 16c0af88-d1e2-11f0-94a7-001a4af901a5 https://dirros.openscience.si/Dokument.php?lang=slv&id=36651 Univerzitetni klinični center Ljubljana 0 0 0