20.500.12556/DiRROS-24542 Predictors of loneliness in Parkinson's disease and craniocervical dystonia Background Loneliness is a state in which an individual feels socially isolated due to deficiencies in the quantity or quality of social relationships and interaction. To date very little is known about loneliness in Parkinson's disease (PD) and focal/segmental craniocervical dystonia (FSCD). Objectives To explore whether level of loneliness is disease-specific by comparing PD, FCSD and healthy controls (HCs), and to define predictors of loneliness in both PD and FSCD. Methods Eighty-two people with PD, 63 people with FSCD and 50 HC were surveyed. The UCLA Loneliness Scale was used to assess loneliness. Various non-motor symptoms, psychosocial variables and measures of subjective well-being were assessed and used as potential predictors of loneliness. Results There was no significant difference in reported levels of loneliness between people with PD and matched HCs, and between people with PD and people with FSCD, but people with FSCD reported higher levels of loneliness than HCs (p = 0.018). Perceived stigma predicted loneliness in both disease groups (p < 0.001). Additionally, non-motor symptoms (p = 0.006), lack of optimism (p = 0.015) and practical social support (p = 0.006) predicted loneliness in people with PD. Patients with PD and FSCD with higher perceived stigma levels felt lonelier (p < 0.001), as did female patients with PD (p = 0.004), younger patients with FSCD (p = 0.007) and older patients with PD (p = 0.023). Conclusions We identified important predictors of loneliness in PD and FSCD. The identified age- and gender-specific differences in loneliness in people with PD and FSCD contribute to our better understanding of this complex and not yet fully understood concept. loneliness Parkinson's disease focal/segmental craniocervical dystonia optimism and stigma true false true Angleški jezik Ni določen Neznano 2025-12-04 14:36:20 2025-12-04 14:36:20 2025-12-06 03:42:14 0000-00-00 00:00:00 2025 0 0 Nasl. z nasl. zaslona; Opis z dne 28. 5. 2025; str. 1302-1312 iss. 9 Vol. 12 2025 0000-00-00 Zaloznikova Objavljeno apc 0000-00-00 0000-00-00 0000-00-00 616.858 2330-1619 10.1002/mdc3.70098 237552643 RAZ_Shahmoon_Suzette_2025.pdf RAZ_Shahmoon_Suzette_2025.pdf 1 D6B9B16DA5C8707D923F7943AC63C557 1f03afbf3d53ec03f68b8613bd795351cc488ca8835f09e7720c3a8260635913 60cbd7bb-d116-11f0-94a7-001a4af901a5 https://dirros.openscience.si/Dokument.php?lang=slv&id=36603 https://movementdisorders.onlinelibrary.wiley.com/doi/10.1002/mdc3.70098 1 39d92bf4-d116-11f0-94a7-001a4af901a5 https://dirros.openscience.si/Dokument.php?lang=slv&id=36602 Univerzitetni klinični center Ljubljana 0 0 0