20.500.12556/DiRROS-24412 Association of tumor-infiltrating lymphocytes and inflammation status with survival outcome in patients with high-grade serous ovarian carcinoma In this study, we investigated the association between tumor-infiltrating lymphocytes (TILs), inflammation status, and progression-free survival (PFS) in patients with primary high-grade serous ovarian carcinoma (HGSC). We assessed the percentages of different intraepithelial and stromal TIL subtypes using both manual and digital methods, following established recommendations for TIL assessment. In addition, we evaluated inflammation status through several immune scores, including the pan-immune-inflammation value (PIV). Our results suggest that stromal CD3+ and CD8+ TILs, as well as PIV, may serve as potential prognostic indicators in HGSC, as they remained potential independent markers in multivariate analysis. ovarian carcinoma high-grade serous ovarian carcinoma prognostic factors rak jajčnikov visoko serozni rak jajčniokov napovedni dejavniki true false true MDPI, Basel, Switzerland Basel, Switzerland Angleški jezik Slovenski jezik by Authors Neznano 2025-11-27 03:58:43 2025-12-05 11:26:38 2025-12-06 03:38:40 0000-00-00 00:00:00 2025 0 Basel 0 Nasl. z nasl. zaslona; Opis vira z dne 9. 7. 2025; str. 2269-1-2269-21 no. 4 Vol. 17 2025 0000-00-00 Zaloznikova Objavljeno apc 2025-05-26 2025-07-05 2025-07-08 618.1 2072-6694 10.3390/cancers17142269 241873923 https://www.mdpi.com/2072-6694/17/14/2269 1 fd023698-cb3c-11f0-94a7-001a4af901a5 https://dirros.openscience.si/Dokument.php?lang=slv&id=36338 Onkološki inštitut Ljubljana 0 0 0