20.500.12556/DiRROS-24034 The effect of a 12-week dietary intake of food supplements containing collagen and MSM on dermis density and other skin parameters A double-blind, placebo-controlled, randomised four-way study comparing the efficacy of three test products Vpliv 12-tedenske prehranske uporabe prehranskih dopolnil s kolagenom in MSM na gostoto dermisa ter druge parametre kože: Dvojno slepa, s placebom kontrolirana, randomizirana študija v štirih smereh, ki primerja učinkovitost treh testnih izdelkov Dietary supplementation with collagen has been gaining popularity as an anti-ageing remedy. The aim of this randomised, double-blind placebo-controlled four-way study was to investigate and compare the effects of 12-week daily dietary supplementation with products containing 10 g hydrolysed fish collagen (HC) or a combination of 5 g or 10 g HC with 1.5 g methylsulphonylmethane (MSM) on dermis density in healthy human subjects. The secondary objectives were to investigate the effects on a variety of other skin parameters. The study results showed improved dermis density, skin texture and reduced wrinkles for all the active products. However, products containing MSM were superior in the improvement of skin thickness and roughness, and a higher dose of HC combined with MSM was crucial for improvement in hydration. On the other hand, no significant effects of the supplementation on viscoelasticity and transepidermal water loss were determined with any of the products. collagen MSM ageing-skin density texture wrinkles kolagen MSM staranje kože gostota tekstura gube true false true Angleški jezik Slovenski jezik © 2023 The Authors. Published by Elsevier Ltd. Neznano 2025-11-07 12:55:02 2025-11-10 10:17:05 2025-11-11 03:47:05 0000-00-00 00:00:00 2023 0 0 Nasl. z nasl. zaslona; Opis vira z dne 22. 12. 2023; Nasl. in besedilo povzetka v slov. podal avtor; Dodajanje kolagena prehrane je vse bolj priljubljeno, dokazi na tem področju pa so omejeni. Cilj randomizirane, dvojno slepe, s placebom kontrolirane študije je bil raziskati in primerjati učinke 12-tedenskega dnevnega dopolnjevanja prehrane z izdelki, ki vsebujejo 10 g hidroliziranega ribjega kolagena (HC) ali kombinacijo 5 g ali 10 g HC z 1,5 g metilsulfonilmetana (MSM) na gostoto dermisa pri zdravih ljudeh. Sekundarni cilji so vključevali raziskovanje učinkov na različne druge parametre kože. Rezultati študije so pokazali izboljšano gostoto dermisa, teksturo kože in zmanjšanje gub za vse testirane aktivne izdelke. Izdelki z MSM so se izkazali kot učinkovitejše pri izboljšanju debeline in hrapavosti kože, višji odmerek HC v kombinaciji s MSM pa je bil ključen za izboljšanje vlažnosti. Po drugi strani pri nobenem od testiranih izdelkov nismo ugotovili pomembnih učinkov dopolnjevanja na viskoelastičnost in transepidermalno izgubo vode.; str. [1]-13 Vol. 110, [article no.] 1253341 Nov. 2023 0000-00-00 Zaloznikova Objavljeno NiDoloceno 0000-00-00 0000-00-00 2023-11-01 612.39:613.2 2214-9414 10.1016/j.jff.2023.105838 178701827 https://www.sciencedirect.com/science/article/pii/S1756464623004383 1 98ad2a94-bbd0-11f0-94a7-001a4af901a5 https://dirros.openscience.si/Dokument.php?lang=slv&id=35710 RAZ_Pogacnik_Tina_2023.pdf RAZ_Pogacnik_Tina_2023.pdf 1 C43FA2C98A5CED4C98EAF0727D060211 0fc941529c0387eaa9c759537a3a601d397e0fbde1bf932e21c88c7367fe0802 dbae65fc-be15-11f0-94a7-001a4af901a5 https://dirros.openscience.si/Dokument.php?lang=slv&id=35733 Inštitut za nutricionistiko 0 0 0