20.500.12556/DiRROS-23976 Synthesis of a water-soluble BODIPY for targeting and assessing the function of endoplasmic reticulum We report here on a straightforward methodology to synthesize a new water-soluble fluorescent probe TrisBODIPY-OH 1 that contains three pH-independent hydrophilic arms. This probe has been prepared by exploiting a synthetic strategy that includes as a key step the combination of a Cu(I)-catalyzed azide−alkyne cycloaddition (CuAAC) and a Sonogashira cross-coupling in a sequential one-pot approach. Tris-BODIPY-OH 1 provides a significant advancement in the field by expanding the BODIPY toolbox with a biocompatible water-soluble probe, which can be used to specifically label and assess the function of the endoplasmic reticulum. BODIPY Sonogashira cross-coupling azide-alkyne cycloaddition endoplasmic reticulum organelle labeling chick chorioallantoic membrane model true false true American Chemical Society ZDA Angleški jezik Ni določen © 2025 The Authors. Neznano 2025-10-30 13:28:52 2025-10-30 13:28:53 2025-10-31 03:39:55 0000-00-00 00:00:00 2025 0 0 Soavtorji: Giacomo Biagotti, Tommy Chastel, Serena Filiberti, Hana Kokot, Francesca Mancusi, Maja Žežlina, Layal Rajeh, Iztok Urbančič, Stéphane Bodin, idr.; Nasl. z nasl. zaslona; Opis vira z dne 30. 10. 2025; str. 895-905 iss. 5 Vol. 5 2025 0000-00-00 Zaloznikova Objavljeno NiDoloceno 2025-06-04 2025-07-25 2025-08-04 547 2694-2437 10.1021/acsbiomedchemau.5c00142 255414531 https://pubs.acs.org/doi/pdf/10.1021/acsbiomedchemau.5c00142?ref=article_openPDF 1 007f527e-b58c-11f0-9bb7-001a4af901a5 https://dirros.openscience.si/Dokument.php?lang=slv&id=35616 RAZ_Tricomi_Jacopo_2025.pdf RAZ_Tricomi_Jacopo_2025.pdf 1 AA04E3F40A78B5047FF12EDA0395DFEB 3061bd45d291cb9883e49e25f68bafdaa8785faeba332c22de3afd52af915a1b 493fe716-b58c-11f0-9bb7-001a4af901a5 https://dirros.openscience.si/Dokument.php?lang=slv&id=35617 Institut Jožef Stefan 0 0 0