20.500.12556/DiRROS-23053 Priporočila za sistemsko onkološko in radioterapevtsko zdravljenje rakov biliarnega trakta Recommendations for systemic oncological and radiation treatment of the biliary tract cancers Raki biliarnega trakta so redka in heterogena skupina z naraščajočo incidenco in visoko umrljivostjo. Imajo slabo prognozo s celokupnim preživetjem manj od 1 leta. Nova dognanja o molekularno genetski heterogenosti rakov biliarnega trakta in novi terapevtskih pristopi omogočajo tem bolnikom daljša preživetja in boljšo kvaliteto življenja. V Priporočilih so predstavljena najnovejša priporočila za sistemsko onkološko zdravljenje in radioterapijo te skupine rakov, med katere po mednarodnih propročilih sedaj prištevamo karcinom žolčnika, intrahepatalne holangiokarcinome in ekstrahepatične holangiokarcinome, s perihilarnim holangiokarcinomom in karcinomom distalnega žolčevoda. Priporočila za sistemsko zdravljenje so povzeta in pripravljena na podlagi mednarodnih priporočil, ameriških, National Comprehensive Cancer Network (NCCN) in evropskih, Evropskega združenja za internistično onkologijo – European Society of Medical oncology (ESMO). Biliary tract cancers are a rare and heterogeneous group with increasing incidence and high mortality. They have a poor prognosis with an overall survival of less than 1 year. New insights into the molecular genetic heterogeneity of biliary tract cancers and new therapeutic approaches allow these patients to survive longer and have a better quality of life. The Recommendations present the latest recommendations for systemic oncological treatment and radiotherapy of this group of cancers, which, according to international agreements, now include gallbladder carcinoma, intrahepatic cholangiocarcinoma and extrahepatic cholangiocarcinoma, with perihilar cholangiocarcinoma and carcinoma of the distal bile duct. The recommendations for systemic treatment are summarized and prepared on the basis of international recommendations, American National Comprehensive Cancer Network (NCCN) and European, European Association for Internal Oncology - European Society of Medical Oncology (ESMO). raki biliarnega trakta sistemsko zdravljenje priporočila true false true Slovenski jezik Angleški jezik Neznano 2025-07-18 11:36:54 2025-07-18 11:36:54 2025-10-24 03:53:01 0000-00-00 00:00:00 2025 0 0 str. 56-61 št. 1 Letn. 29 jun. 2025 0000-00-00 Zaloznikova Objavljeno NiDoloceno 0000-00-00 0000-00-00 2025-06-01 616.3 1408-1741 10.25670/oi2025-008on 239262467 RAZ_Brecelj_Erik_2025.pdf RAZ_Brecelj_Erik_2025.pdf 1 5E8C270981FF4C406557BB9224E73037 ef8aaa5f9fe032f8304688c23fd5dcf539b139ddc1e11d64a98a0c0282e8a0cc e9dfadd3-63ba-11f0-9bb7-001a4af901a5 https://dirros.openscience.si/Dokument.php?lang=slv&id=33793 Onkološki inštitut Ljubljana Onkologija : strokovni časopis za zdravnike 0 0 0