20.500.12556/DiRROS-22948 Antibacterial and antibiofouling activities of carbon polymerized dots/polyurethane and c[sub]60/polyurethane composite films The cost of treatment of antibiotic-resistant pathogens is on the level of tens of billions of dollars at the moment. It is of special interest to reduce or solve this problem using antimicrobial coatings, especially in hospitals or other healthcare facilities. The bacteria can transfer from medical staff or contaminated surfaces to patients. In this paper, we focused our attention on the antibacterial and antibiofouling activities of two types of photodynamic polyurethane composite films doped with carbon polymerized dots (CPDs) and fullerene C60. Detailed atomic force, electrostatic force and viscoelastic microscopy revealed topology, nanoelectrical and nanomechanical properties of used fillers and composites. A relationship between the electronic structure of the nanocarbon fillers and the antibacterial and antibiofouling activities of the composites was established. Thorough spectroscopic analysis of reactive oxygen species (ROS) generation was conducted for both composite films, and it was found that both of them were potent antibacterial agents against nosocomial bacteria (Klebsiela pneumoniae, Proteus mirabilis, Salmonela enterica, Enterococcus faecalis, Enterococcus epidermis and Pseudomonas aeruginosa). Antibiofouling testing of composite films indicated that the CPDs/PU composite films eradicated almost completely the biofilms of Pseudomonas aeruginosa and Staphylococcus aureus and about 50% of Escherichia coli biofilms mikroskopija fotodinamika antibakterijsko true false true MDPI Švica Angleški jezik Slovenski jezik © 2024 by the authors. Neznano 2025-07-11 09:49:46 2025-07-11 09:49:46 2025-10-24 03:52:48 0000-00-00 00:00:00 2024 0 0 Iss. 3 Vol. 15 2024 0000-00-00 Zaloznikova Objavljeno NiDoloceno 2024-02-08 2024-03-14 2024-03-17 539 2079-4983 10.3390/jfb15030073 241940995 RAZ_Markovic_Zoran_M._2024.pdf RAZ_Markovic_Zoran_M._2024.pdf 1 8ECB1FCEE2C9EEB8AC89DC61F1BC0B57 5e020a258f6d54ffcb6ed183d66d223d7765de529251fb6bc5a374691c546486 3fca19c7-5e2c-11f0-9bb7-001a4af901a5 https://dirros.openscience.si/Dokument.php?lang=slv&id=33485 Institut Jožef Stefan 0 0 0