20.500.12556/DiRROS-22491 Cold-induced anaphylaxis new insights into clinical and genetic characteristics The pathogenesis of cold urticaria (ColdU) and cold-induced anaphylaxis (ColdA) remains poorly understood, and ColdA is underrepresented in anaphylaxis literature. Laboratory features to guide management are largely unknown. This study evaluated basal serum tryptase (BST) and total immunoglobulin E (IgE) levels in ColdU and ColdA, their associations with clinical features, and the utility of testing for the KIT p.D816V variant in blood leukocytes and hereditary a-tryptasemia (HaT). anaphylaxis cold urticaria hereditary α-tryptasemia KIT p.D816V mast cell total IgE tryptase anafilaksija urtikarija zaradi mraza dedna α-triptazemija KIT p.D816V mastociti skupni IgE triptaza true false true Frontiers Research Foundation, 2010- Frontiers in immunology Angleški jezik Slovenski jezik © 2025 Bizjak, Korošec, Košnik, Šelb, Bidovec-Stojkovič, Svetina, Zver, Dinevski and Rijavec. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms. Neznano 2025-05-21 11:00:44 2025-05-21 11:00:44 2025-10-24 03:51:22 0000-00-00 00:00:00 2025 0 0 Nasl. z nasl. zaslona; Opis vira z dne 18. 3. 2025; str. [1-11] Vol. 16 2025 0000-00-00 Zaloznikova Objavljeno NiDoloceno 2025-01-10 2025-02-11 2025-02-21 616-097 1664-3224 10.3389/fimmu.2025.1558284 229318403 https://www.frontiersin.org/journals/immunology/articles/10.3389/fimmu.2025.1558284/full 1 15f85bfa-3622-11f0-963a-001a4af901a5 https://dirros.openscience.si/Dokument.php?lang=slv&id=32494 RAZ_Bizjak_Mojca_2025.pdf RAZ_Bizjak_Mojca_2025.pdf 1 72BFE2B00525BBD32A80350B4BC2FFE4 77dc0ce1dac0aceeab43da90fd65aa7ffcd7fea03dfb8163f4743c467fbd76c9 0e61f235-3623-11f0-963a-001a4af901a5 https://dirros.openscience.si/Dokument.php?lang=slv&id=32497 Univerzitetna klinika za pljučne bolezni in alergijo Golnik 0 0 0