20.500.12556/DiRROS-20896 Cold plasma within a stable supercavitation bubble - a breakthrough technology for efficient inactivation of viruses in water Water scarcity, one of the most pressing challenges we face today, has developed for many reasons, including the increasing number of waterborne pollutants that affect the safety of the water environment. Waterborne human, animal and plant viruses represent huge health, environmental, and financial burden and thus it is important to efficiently inactivate them. Therefore, the main objective of this study was to construct a unique device combining plasma with supercavitation and to evaluate its efficiency for water decontamination with the emphasis on inactivation of viruses. High inactivation (>5 log10 PFU/mL) of bacteriophage MS2, a human enteric virus surrogate, was achieved after treatment of 0.43 L of recirculating water for up to 4 min. The key factors in the inactivation were short-lived reactive plasma species that damaged viral RNA. Water treated with plasma for a short time required for successful virus inactivation did not cause cytotoxic effects in the in vitro HepG2 cell model system or adverse effects on potato plant physiology. Therefore, the combined plasma-supercavitation device represents an environmentally-friendly technology that could provide contamination-free and safe water. cold plasma hydrodynamic cavitation supercavitation virus inactivation water decontamination toxicity assays hladna plazma hidrodinamična kavitacija superkavitacija inaktivacija virusa dekontaminacija vode testi toksičnosti true false true Angleški jezik Slovenski jezik Neznano 2024-11-28 11:31:55 2024-11-28 11:31:56 2024-11-29 03:38:14 0000-00-00 00:00:00 2023 0 0 Soavtorji: David Dobnik, Ion Gutiérrez-Aguirre, Maja Ravnikar, Tamara Košir, Špela Baebler, Alja Štern, Bojana Žegura, Martin Petkovšek, Matevž Dular, Miran Mozetič, Rok Zaplotnik, Gregor Primc; str. 1-10 [art. no] ǂ108285 Vol. 182 Dec. 2023 0000-00-00 Zaloznikova Objavljeno NiDoloceno 0000-00-00 0000-00-00 2023-12-01 533 0160-4120 10.1016/j.envint.2023.108285 170521347 RAZ_Filipic_Arijana_2023.pdf RAZ_Filipic_Arijana_2023.pdf 1 78B75AE51BF204C1C597621ED5662CE7 4fa3e06859e27ad257081f4fa26cef66d40d14b3fb8a29bb5e76f9888022cbc1 19fff53d-ad74-11ef-ba3f-001a4af901a5 https://dirros.openscience.si/Dokument.php?lang=slv&id=29544 RAZ_Filipic_Arijana_2023.docx RAZ_Filipic_Arijana_2023.docx 1 17403612913860B71DD26628CF2EC25F a124685f14a99b8d432fbea25e457873d4097d6d81824b4c5cd6eefe75ef4368 2a6a9c8f-ad74-11ef-ba3f-001a4af901a5 https://dirros.openscience.si/Dokument.php?lang=slv&id=29545 https://doi.org/10.1016/j.envint.2023.108285 0 3ee28e30-ad74-11ef-ba3f-001a4af901a5 https://dirros.openscience.si/Dokument.php?lang=slv&id=29546 Nacionalni inštitut za biologijo 0 0 0