20.500.12556/DiRROS-20150 Editorial brain cancer pathogenesis and data integration Brain tumors are one of the most aggressive malignancies in humans. They can be classified as primary tumors, which arise in the brain, or secondary tumors, which arise elsewhere in the body and initially metastaze the brain. The morbidity and mortality of brain tumors is one of the highest among cancers (Siegel et al., 2023). Of particular concern is that mortality and incidence of brain tumors are increasing, especially in the population under 44 years of age. Brain tumor mortality in this population is 13.4%. For example, primary brain tumors are the most common cancer in children and the leading cause of death in pediatric cancer patients (Gould, 2018). Considering the low survival rate of adult and pediatric brain tumor patients and the detrimental impact on patient quality of life, economic costs, and mortality rates, there is an urgent need to develop more effective therapeutic approaches. Despite major research efforts, there are currently no effective treatment modalities or prevention strategies that would significantly improve the quality of life and disease outcome of brain tumor patients. brain tumor data integration therapeutic resistance biomarkers liquid biopsies možganski tumorji integracija podatkov biološki označevalci biomarkerji rak onkologija true false true Angleški jezik Slovenski jezik Neznano 2024-08-06 14:07:03 2024-08-06 14:07:04 2024-08-07 04:07:26 0000-00-00 00:00:00 2023 0 0 Nasl. z nasl. zaslona; Opis vira z dne 24. 10. 2023; str. 1-2 [article no.] ǂ1298285 Vol. 14 Oct. 2023 0000-00-00 Zaloznikova Objavljeno NiDoloceno 0000-00-00 0000-00-00 2023-10-13 616-006 1664-8021 10.3389/fgene.2023.1298285 169559043 https://doi.org/10.3389/fgene.2023.1298285 1 ab3d23d5-53db-11ef-b487-001a4af901a5 https://dirros.openscience.si/Dokument.php?lang=slv&id=28144 RAZ_Comba_Andrea_2023.pdf RAZ_Comba_Andrea_2023.pdf 1 5A2F00A49AE7D9359667E8BD58863FA9 e013d41d20e0edee59cb986d3ea5fdc7b02a7d6d403477c5a20808f8dac1d59f e46ab08b-53db-11ef-b487-001a4af901a5 https://dirros.openscience.si/Dokument.php?lang=slv&id=28145 Nacionalni inštitut za biologijo 0 0 0