20.500.12556/DiRROS-20067 ELIXIR and toxicology a community in development [version 2; peer review: 2 approved] Toxicology has been an active research field for many decades, with academic, industrial and government involvement. Modern omics and computational approaches are changing the field, from merely disease-specific observational models into target-specific predictive models. Traditionally, toxicology has strong links with other fields such as biology, chemistry, pharmacology, and medicine. With the rise of synthetic and new engineered materials, alongside ongoing prioritisation needs in chemical risk assessment for existing chemicals, early predictive evaluations are becoming of utmost importance to both scientific and regulatory purposes. ELIXIR is an intergovernmental organisation that brings together life science resources from across Europe. To coordinate the linkage of various life science efforts around modern predictive toxicology, the establishment of a new ELIXIR Community is seen as instrumental. In the past few years, joint efforts, building on incidental overlap, have been piloted in the context of ELIXIR. For example, the EU-ToxRisk, diXa, HeCaToS, transQST, and the nanotoxicology community have worked with the ELIXIR TeSS, Bioschemas, and Compute Platforms and activities. In 2018, a core group of interested parties wrote a proposal, outlining a sketch of what this new ELIXIR Toxicology Community would look like. A recent workshop (held September 30th to October 1st, 2020) extended this into an ELIXIR Toxicology roadmap and a shortlist of limited investment-high gain collaborations to give body to this new community. This Whitepaper outlines the results of these efforts and defines our vision of the ELIXIR Toxicology Community and how it complements other ELIXIR activities. toxicology ELIXIR interoperability FAIR toksikologija interoperabilnost podatkovne zbirke true false true Angleški jezik Slovenski jezik Neznano 2024-08-05 12:41:33 2024-08-05 12:41:33 2024-08-07 03:50:41 0000-00-00 00:00:00 2023 0 0 Soavtorji: Rob Stierum, Emma L. Schymanski, Chris T. Evelo, Reza Aalizadeh, Hristo Aladjov, Kasia Arturi, Karine Audouze, Pavel Babica, Karel Berka, Jos Bessems, Ludek Blaha, Evan E. Bolton, Montserrat Cases, Dimitrios Ε. Damalas, Kirtan Dave, Marco Dilger, Thomas Exner, Daan P. Geerke, Roland Grafström, Alasdair Gray, John M. Hancock, Henner Hollert, Nina Jeliazkova, Danyel Jennen , Fabien Jourdan, Pascal Kahlem, Jana Klanova, Jos Kleinjans, Todor Kondic, Boï Kone, Iseult Lynch, Uko Maran, Sergio Martinez Cuesta, Hervé Ménager, Steffen Neumann, Penny Nymark, Herbert Oberacher, Noelia Ramirez, Sylvie Remy, Philippe Rocca-Serra, Reza M. Salek, Brett Sallach, Susanna-Assunta Sansone, Ferran Sanz, Haralambos Sarimveis, Sirarat Sarntivijai, Tobias Schulze, Jaroslav Slobodnik, Ola Spjuth, Jonathan Tedds, Nikolaos Thomaidis, Ralf J.M. Weber, Gerard J.P. van Westen, Craig E. Wheelock, Antony J. Williams, Hilda Witters, Barbara Zdrazil, Anže Županič, Egon L. Willighagen; Nasl. z nasl. zaslona; Opis vira z dne 12. 10. 2023; str. 1-15 art. no. ǂ1129 Vol. 10 2023 0000-00-00 Zaloznikova Objavljeno NiDoloceno 0000-00-00 0000-00-00 2023-10-03 615.9 2046-1402 10.12688/f1000research.74502.2 168137731 https://doi.org/10.12688/f1000research.74502.2 1 8e770d6b-5306-11ef-b487-001a4af901a5 https://dirros.openscience.si/Dokument.php?lang=slv&id=27964 RAZ_Martens_Marvin_2023.pdf RAZ_Martens_Marvin_2023.pdf 1 3822FA428BDAC63CA54FC77E3778046D fc5853edabcf547faa3d4e228a06ffddb8a4df4ef33ea055386aa1d528dbb43c c2e2ad60-5308-11ef-b487-001a4af901a5 https://dirros.openscience.si/Dokument.php?lang=slv&id=27968 Nacionalni inštitut za biologijo 0 0 0