20.500.12556/DiRROS-19655 Effects of oils and solid fats on blood lipids a systematic review and network meta-analysis The aim of this network meta-analysis (NMA) is to compare the effects of different oils/solid fats on blood lipids. Literature searches were performed until March 2018. Inclusion criteria were as follows: i) randomized trial (≥3 weeks study length) comparing at least two of the following oils/solid fats: safflower, sunflower, rapeseed, hempseed, flaxseed, corn, olive, soybean, palm, and coconut oil, and lard, beef-fat, and butter; ii) outcomes LDL-cholesterol (LDL-C), total cholesterol (TC), HDL-cholesterol (HDL-C), and triacylglycerols (TGs). A random dose-response (per 10% isocaloric exchange) NMA was performed and surface under the cumulative ranking curve (SUCRA) was estimated. Fifty-four trials were included in the NMA. Safflower oil had the highest SUCRA value for LDL-C (82%) and TC (90%), followed by rapeseed oil (76% for LDL-C, 85% for TC); whereas, palm oil (74%) had the highest SUCRA value for TG, and coconut oil (88%) for HDL-C. Safflower, sunflower, rapeseed, flaxseed, corn, olive, soybean, palm, and coconut oil as well beef fat were more effective in reducing LDL-C (−0.42 to −0.23 mmol/l) as compared with butter. Despite limitations in these data, our NMA findings are in line with existing evidence on the metabolic effects of fat and support current recommendations to replace high saturated-fat food with unsaturated oils. cardiovascular disease evidence synthesis fatty acids bolezni srca in ožilja sinteza dokazov maščobne kisline meta-analize true false true Angleški jezik Slovenski jezik Neznano 2024-07-23 03:55:16 2024-07-24 14:07:09 2024-07-25 04:14:53 0000-00-00 00:00:00 2018 0 0 str. 1771-1782 iss. 9 Vol. 59 2018 0000-00-00 Zaloznikova Objavljeno NiDoloceno 0000-00-00 0000-00-00 2018-09-01 577 0022-2275 10.1194/jlr.P085522 33548803 https://www.jlr.org/content/59/9/1771.long 1 d83e2be5-4885-11ef-b487-001a4af901a5 https://dirros.openscience.si/Dokument.php?lang=slv&id=27146 RAZ_Schwingshackl_Lukas_2018.pdf RAZ_Schwingshackl_Lukas_2018.pdf 1 C7E0B7B57566AAAEFC29F57E0472B530 de1954ba0cbaeaeed5fe94c1fb26aaf84f37bb8feb012e45e389e5f3f845e48a b014351c-49a4-11ef-b487-001a4af901a5 https://dirros.openscience.si/Dokument.php?lang=slv&id=27344 Nacionalni inštitut za biologijo 0 0 0