20.500.12556/DiRROS-19608 The importance of flaps in reconstruction of locoregionally advanced lateral skull-base cancer defects a tertiary otorhinolaryngology referral centre experience Background. The aim of the study was to identify the value of extensive resection and reconstruction with flaps in the treatment of locoregionally advanced lateral skull-base cancer.Patients and methods. The retrospective case review of patients with lateral skull-base cancer treated surgically with curative intent between 2011 and 2019 at a tertiary otorhinolaryngology referral centre was made. Results. Twelve patients with locoregionally advanced cancer were analysed. Lateral temporal bone resection was performed in nine (75.0%), partial parotidectomy in six (50.0%), total parotidectomy in one (8.3%), ipsilateral selective neck dissection in eight (66.7%) and ipsilateral modified radical neck dissection in one patient (8.3%). The defect was reconstructed with anterolateral thigh free flap, radial forearm free flap or pectoralis major myocutaneous flap in two patients (17.0%) each. Mean overall survival was 3.1 years (SD = 2.5) and cancer-free survival rate 100%. At the data collection cut-off, 83% of analysed patients and 100% of patients with flap reconstruction were alive. Conclusions. Favourable local control in lateral skull-base cancer, which mainly involves temporal bone is achieved with an extensive locoregional resection followed by free or regional flap reconstruction. Universal cancer registry should be considered in centres treating this rare disease to alleviate analysis and multicentric research. temporal bone microsurgery parotid region free tissue flaps neoplasm staging ear mikrokirurgija neoplazme uho temporalna kost senčnica true false true Association of Radiology and Oncology Ljubljana Angleški jezik Slovenski jezik by Authors Neznano 2024-07-22 14:05:31 2024-07-22 14:05:31 2024-07-23 03:55:55 0000-00-00 00:00:00 2021 0 0 Sovtorji: Peter Pukl, Ales Groselj, Aleksander Anicin, Primoz Strojan, Saba Battelino; str. 323-332, VIII no. 3 Vol. 55 2021 0000-00-00 Zaloznikova Objavljeno NiDoloceno 0000-00-00 0000-00-00 2021-01-01 617 1318-2099 10.2478/raon-2021-0012 59567619 RAZ_Vozel_Domen_2021.pdf RAZ_Vozel_Domen_2021.pdf 1 756D9F48D002755D9C496E0F7229AC53 cfa808de0b96075a9082d960e1cd32dafcda8d9a06580508d8c9c17d5ddf8c17 188ba452-4812-11ef-b487-001a4af901a5 https://dirros.openscience.si/Dokument.php?lang=slv&id=27103 Onkološki inštitut Ljubljana 0 0 0