20.500.12556/DiRROS-19587 Fifty Aureobasidium pullulans genomes reveal a recombining polyextremotolerant generalist The black yeast Aureobasidium pullulans is a textbook example of a generalistic and ubiquitous fungus thriving in a wide variety of environments. To investigate whether A. pullulans is a true generalist, or alternatively, whether part of its versatility can be attributed to intraspecific specialization masked by cryptic diversification undetectable by traditional phylogenetic analyses, we sequenced and analysed the genomes of 50 strains of A. pullulans from different habitats and geographic locations. No population structure was observed in the sequenced strains. Decay of linkage disequilibrium over shorter physical distances (<100 bp) than in many sexually reproducing fungi indicates a high level of recombination in the species. A homothallic mating locus was found in all of the sequenced genomes. Aureobasidium pullulans appears to have a homogeneous population genetics structure, which is best explained by good dispersal and high levels of recombination. This means that A. pullulans is a true generalist that can inhabit different habitats without substantial specialization to any of these habitats at the genomic level. Furthermore, in the future, the high level of A. pullulans recombination can be exploited for the identification of genomic loci that are involved in the many biotechnologically useful traits of this black yeast. black yeast genome true false true Angleški jezik Ni določen Neznano 2024-07-20 04:01:59 2024-07-24 09:09:27 2024-07-25 04:14:44 0000-00-00 00:00:00 2019 0 0 str. 3638-3652 iss. 10 Vol. 21 2019 0000-00-00 Zaloznikova Objavljeno NiDoloceno 0000-00-00 0000-00-00 2019-10-01 577.21 1462-2912 10.1111/1462-2920.14693 5158991 https://doi.org/10.1111/1462-2920.14693 1 533847d0-462b-11ef-b487-001a4af901a5 https://dirros.openscience.si/Dokument.php?lang=slv&id=27041 RAZ_Gostincar_Cene_2019.pdf RAZ_Gostincar_Cene_2019.pdf 1 C95B2FF28E62084A44D22064A2D84360 cd62d06aa2cbbdbec0bca33a86a52edcf0b84adc88756cfe08ab8df34b9e3966 3a79ec00-497b-11ef-b487-001a4af901a5 https://dirros.openscience.si/Dokument.php?lang=slv&id=27247 Nacionalni inštitut za biologijo 0 0 0