20.500.12556/DiRROS-19573 MapMan4 a refined protein classification and annotation framework applicable to multi-omics data analysis Genome sequences from over 200 plant species have already been published, with this number expected to increase rapidly due to advances in sequencing technologies. Once a new genome has been assembled and the genes identified, the functional annotation of their putative translational products, proteins, using ontologies is of key importance as it places the sequencing data in a biological context. Furthermore, to keep pace with rapid production of genome sequences, this functional annotation process must be fully automated. Here we present a redesigned and significantly enhanced MapMan4 framework, together with a revised version of the associated online Mercator annotation tool. Compared with the original MapMan, the new ontology has been expanded almost threefold and enforces stricter assignment rules. This framework was then incorporated into Mercator4, which has been upgraded to reflect current knowledge across the land plant group, providing protein annotations for all embryophytes with a comparably high quality. The annotation process has been optimized to allow a plant genome to be annotated in a matter of minutes. The output results continue to be compatible with the established MapMan desktop application. genome sequences MapMan4 true false true Angleški jezik Ni določen Neznano 2024-07-20 04:00:32 2024-07-23 14:17:14 2024-07-24 03:47:58 0000-00-00 00:00:00 2019 0 0 str. 879-892 iss. 6 Vol. 12 2019 0000-00-00 Zaloznikova Objavljeno NiDoloceno 0000-00-00 0000-00-00 2019-06-03 577.2 1674-2052 10.1016/j.molp.2019.01.003 4958799 RAZ_Schwacke_Rainer_2019.pdf RAZ_Schwacke_Rainer_2019.pdf 1 8987C1C897F30CC63616D997F523E452 ad148116c6afb8cae4dba2b9a48daedd0b8b22f35296a8e0c7e0bcd31178425c ac4f2381-48dd-11ef-b487-001a4af901a5 https://dirros.openscience.si/Dokument.php?lang=slv&id=27197 https://doi.org/10.1016/j.molp.2019.01.003 0 c92db796-48dd-11ef-b487-001a4af901a5 https://dirros.openscience.si/Dokument.php?lang=slv&id=27198 Nacionalni inštitut za biologijo 0 0 0