20.500.12556/DiRROS-19567 Physical activity and cancer risk. Actual knowledge and possible biological mechanisms Scientific evidence has shown that an increase in regular physical activity is associated with a decrease in the development of many types of cancer. Potential mechanisms that link physical activity to reduced cancer risk include a decrease in systemic inflammation, hyperinsulinemia, insulin-like growth factor (IGF-I), sex hormones, pro-inflammatory leptin and other obesity-related cytokines, and a significant increase in anti-inflammatory adiponectin levels. In addition, physical activity improves immune function and the composition and diversity of the gastrointestinal microbiota. Moderate physical activity is important for cancer protection, but the most significant changes in the inflammatory profile are conferred by physical activity performed at higher intensities. Thus, there is a need for further investigation into the type, intensity, and duration of physical activity for the prevention of some types of cancer and the development of effective recommendations. telesna aktivnost rak vnetni in protivnetni citokini biološki mehanizmi true false true Association of Radiology and Oncology Ljubljana Angleški jezik Slovenski jezik by Authors Neznano 2024-07-19 13:42:07 2024-07-19 13:42:07 2024-07-20 04:03:09 0000-00-00 00:00:00 2021 0 0 str. 7-17, I no. 1 Vol. 55 2021 0000-00-00 Zaloznikova Objavljeno NiDoloceno 0000-00-00 0000-00-00 2021-01-01 616-006 1318-2099 10.2478/raon-2020-0063 46741763 https://sciendo.com/article/10.2478/raon-2020-0063 1 2c2ede91-45b3-11ef-b487-001a4af901a5 https://dirros.openscience.si/Dokument.php?lang=slv&id=27016 RAZ_Jurdana_Mihaela_2021.pdf RAZ_Jurdana_Mihaela_2021.pdf 1 7DF121142ACD1BE57FA3D47F8F13EF44 ffd4444c9d942e28d33b1ed152cbf616916d8e4e6945425662866bf002a27a54 69bbf2b1-45b3-11ef-b487-001a4af901a5 https://dirros.openscience.si/Dokument.php?lang=slv&id=27017 Onkološki inštitut Ljubljana 0 0 0