20.500.12556/DiRROS-19539 Minimum Information for Reporting on the Comet Assay (MIRCA) recommendations for describing comet assay procedures and results The comet assay is a widely used test for the detection of DNA damage and repair activity. However, there are interlaboratory differences in reported levels of baseline and induced damage in the same experimental systems. These differences may be attributed to protocol differences, although it is difficult to identify the relevant conditions because detailed comet assay procedures are not always published. Here, we present a Consensus Statement for the Minimum Information for Reporting Comet Assay (MIRCA) providing recommendations for describing comet assay conditions and results. These recommendations differentiate between ‘desirable’ and ‘essential’ information: ‘essential’ information refers to the precise details that are necessary to assess the quality of the experimental work, whereas ‘desirable’ information relates to technical issues that might be encountered when repeating the experiments. Adherence to MIRCA recommendations should ensure that comet assay results can be easily interpreted and independently verified by other researchers. Komet test genotoksičnost DNA poškodbe true false true Angleški jezik Slovenski jezik Neznano 2024-07-19 03:44:19 2024-07-22 11:51:57 2024-07-23 03:55:54 0000-00-00 00:00:00 2020 0 0 Nasl. z nasl. zaslona; Opis vira z dne 28. 10. 2020; str. 3817-3826 iss. 12 Vol. 15 2020 0000-00-00 Zaloznikova Objavljeno NiDoloceno 0000-00-00 0000-00-00 2020-10-26 577 1750-2799 10.1038/s41596-020-0398-1 34443523 https://www.nature.com/articles/s41596-020-0398-1 1 a634f1e5-455f-11ef-b487-001a4af901a5 https://dirros.openscience.si/Dokument.php?lang=slv&id=26940 RAZ_Moller_Peter_2020.pdf RAZ_Moller_Peter_2020.pdf 1 4DBE7D6C9B985DCDDE522F3D6A315CAE 5c35258b0c932ca09e512705e74a9ab5bc70fac34eaf9583513514e40373e305 607c7aa1-47ff-11ef-b487-001a4af901a5 https://dirros.openscience.si/Dokument.php?lang=slv&id=27085 Nacionalni inštitut za biologijo 0 0 0