20.500.12556/DiRROS-19507 Cancer-related fatigue causes and current treatment options Fatigue is a symptom commonly experienced by survivors of cancer through all stages of the disease trajectory. Survivors identify fatigue as a significant problem which is not adequately addressed by healthcare providers [1•]. Being fatigued has a greater negative impact on functioning and health-related quality of life (HRQoL) than other symptoms such as pain or depression [2, 3]. Fatigued survivors are more likely to have reduced employment participation [4, 5], greater financial stress [6], and higher healthcare utilization [6, 7]. Moreover, fatigue may reduce survival; feeling fatigued at diagnosis [6, 8] and during survivorship [9] is associated with higher mortality. This review aims to provide a summary on the current state of research on cancer-related fatigue (CRF) of survivors with local disease treated with curative intent. We briefly summarize the prevalence, definition, evaluation, and etiology of CRF. Due to the volume of research on CRF treatments, we provide a non-exhaustive overview of treatments for CRF published within the last 5 years (guidelines, meta-analyses, reviews, randomized trials). cancer-related fatigue cytokines physical activity pharmacologic complementary and alternative medicine true false true Angleški jezik Ni določen Neznano 2024-07-19 03:41:52 2024-07-19 13:55:08 2024-07-20 04:03:07 0000-00-00 00:00:00 2020 0 0 Nasl. z nasl. zaslona; Opis vira z dne 7. 2. 2020; str. 1-19 iss. 2 Vol. 21 2020 0000-00-00 Zaloznikova Objavljeno NiDoloceno 0000-00-00 0000-00-00 2022-03-01 577 1534-6277 10.1007/s11864-020-0707-5 5310543 https://link.springer.com/article/10.1007%2Fs11864-020-0707-5 1 4f050d0f-455f-11ef-b487-001a4af901a5 https://dirros.openscience.si/Dokument.php?lang=slv&id=26916 https://doi.org/10.1007/s11864-020-0707-5 0 c8e5f05a-45b3-11ef-b487-001a4af901a5 https://dirros.openscience.si/Dokument.php?lang=slv&id=27018 RAZ_Thong_Melissa_S._Y._2020.pdf RAZ_Thong_Melissa_S._Y._2020.pdf 1 013F98D1A4E661D58B9C6DD86B0A654D ce168fb7351df3a5fb8256d98579826c6c07357d15880f8485438d0689440c8e 1ed94b40-45b4-11ef-b487-001a4af901a5 https://dirros.openscience.si/Dokument.php?lang=slv&id=27020 RAZ_Thong_Melissa_S._Y._2020.pdf RAZ_Thong_Melissa_S._Y._2020.pdf 1 6EF827370B15BB5040EF176CBF41D67C c6369fd837dd2d41a4b51bc2aa7f174bc5801c4b316f9b8598f5816dfca2b2da d0aa1f78-45b4-11ef-b487-001a4af901a5 https://dirros.openscience.si/Dokument.php?lang=slv&id=27022 Nacionalni inštitut za biologijo 0 0 0