20.500.12556/DiRROS-19483 Plastic-degrading potential across the global microbiome correlates with recent pollution trends Biodegradation is a plausible route toward sustainable management of the millions of tons of plastic waste that have accumulated in terrestrial and marine environments. However, the global diversity of plastic-degrading enzymes remains poorly understood. Taking advantage of global environmental DNA sampling projects, here we constructed hidden Markov models from experimentally verified enzymes and mined ocean and soil metagenomes to assess the global potential of microorganisms to degrade plastics. By controlling for false positives using gut microbiome data, we compiled a catalogue of over 30,000 nonredundant enzyme homologues with the potential to degrade 10 different plastic types. While differences between the ocean and soil microbiomes likely reflect the base compositions of these environments, we find that ocean enzyme abundance increases with depth as a response to plastic pollution and not merely taxonomic composition. By obtaining further pollution measurements, we observed that the abundance of the uncovered enzymes in both ocean and soil habitats significantly correlates with marine and country-specific plastic pollution trends. Our study thus uncovers the earth microbiome's potential to degrade plastics, providing evidence of a measurable effect of plastic pollution on the global microbial ecology as well as a useful resource for further applied research. bioinformatika okoljska mikrobiologija mikrobna ekologija onesnaženje s plastiko true false true Angleški jezik Slovenski jezik Neznano 2024-07-18 03:52:28 2024-07-19 12:10:27 2024-07-20 04:03:04 0000-00-00 00:00:00 2021 0 0 Nasl. z nasl. zaslona; Opis vira z dne 26. 1. 2022; Sodelavci: Mariia Kokina, Sara Jonasson, Francisco Zorrilla, Aleksej Zelezniaka; str. 1-15 iss. 5 Vol. 12 26. Oct. 2021 0000-00-00 Zaloznikova Objavljeno NiDoloceno 0000-00-00 0000-00-00 2021-10-26 579 2150-7511 10.1128/mBio.02155-21 95090435 https://journals.asm.org/doi/epub/10.1128/mBio.02155-21 1 a31f5dbc-4497-11ef-b487-001a4af901a5 https://dirros.openscience.si/Dokument.php?lang=slv&id=26883 RAZ_Zrimec_Jan_2021.pdf RAZ_Zrimec_Jan_2021.pdf 1 C98F3B963F417C1F3750DDE2C2493A7B 75d0f73668b3dfa1f8866bc7b4a13a01ff7029fb3ae74ec2526b4ec50f334ff0 c32f12d0-45a6-11ef-b487-001a4af901a5 https://dirros.openscience.si/Dokument.php?lang=slv&id=26997 Nacionalni inštitut za biologijo 0 0 0