20.500.12556/DiRROS-19301 Adrenal vein sampling for primary aldosteronism a 15-year national referral center experience Background Adrenal vein sampling (AVS) is essential for diagnostics of primary aldosteronism, distinguishing unilateral from bilateral disease and determining treatment options. We reviewed the performance of AVS for primary aldosteronism at our center during first 15 years, comparing the initial period to the period after the introduction of a dedicated radiologist. Additionally, AVS outcomes were checked against CT findings and the proportion of operated patients with proven unilateral disease was estimated. Patients and methods A retrospective cross-sectional study conducted at the national endocrine referral center included all patients with primary aldosteronism who underwent AVS after its introduction in 2004 until the end of 2018. AVS was performed sequentially during Synacthen infusion. When the ratio of cortisol concentrations from adrenal vein and inferior vena cava was at least 5, AVS was considered successful. Results Data from 235 patients were examined (168 men; age 32%73, median 56 years; BMI 18%48, median 30.4 kg/ m2). Average number of annual AVS procedures increased from 7 in the 2004%2011 period to 29 in the 2012%2018 period (p < 0.001). AVS had to be repeated in 10% of procedures; it was successful in 77% of procedures and 86% of patients. The proportion of patients with successful AVS (92% in 2012%2018 vs. 66% in 2004%2011, p < 0.001) and of successful AVS procedures (82% vs. 61%, p < 0.001) was statistically significantly higher in the recent period. Conclusions Number of AVS procedures and success rate at our center increased over time. Introduction of a dedicated radiologist and technical advance expanded and improved the AVS practice. angiography adrenal gland endocrine disorders angiografija nadledvična žleza endokrine motnje true false true Association of Radiology and Oncology Ljubljana Angleški jezik Slovenski jezik by Authors Neznano 2024-07-15 08:58:34 2024-07-15 08:58:34 2024-07-16 03:45:12 0000-00-00 00:00:00 2020 0 0 Soavtorji: Mojca Jensterle, Gaj Vidmar, Rok Vrckovnik, Pavel Berden and Milenko Stankovic; str. 409-418, III no. 4 Vol. 54 2020 0000-00-00 Zaloznikova Objavljeno NiDoloceno 0000-00-00 0000-00-00 2020-01-01 616.4 1318-2099 10.2478/raon-2020-0052 27351043 https://content.sciendo.com/view/journals/raon/ahead-of-print/article-10.2478-raon-2020-0052/article-10.2478-raon-2020-0052.xml 1 a9edd73e-4277-11ef-b487-001a4af901a5 https://dirros.openscience.si/Dokument.php?lang=slv&id=26616 RAZ_Kocjan_Tomaz_2020.pdf RAZ_Kocjan_Tomaz_2020.pdf 1 9226758DC0FA7939B1C31886976E4405 c3cf789ea8eedbec6dc7925af54d1316a0ca81c16bc06234ceab9535e7286f87 e445d7d0-4277-11ef-b487-001a4af901a5 https://dirros.openscience.si/Dokument.php?lang=slv&id=26617 Onkološki inštitut Ljubljana 0 0 0