20.500.12556/DiRROS-19226 Advances in the management of craniopharyngioma in children and adults Childhood and adult-onset craniopharyngioma is a rare embryogenic tumor of the sellar, suprasellar, and parasellar region. Survival rates are high; however, tumor location and treatment sequalae including endocrine deficits, visual impairment, metabolic complications, cognitive and psychosocial deficits can significantly impair patient%s quality of life. There is considerable controversy regarding the optimal management of craniopharyngiomas. Subtotal resection of the tumor followed by targeted irradiation to avoid further hypothalamic damage is currently indicated. Novel insights in the tumor%s molecular pathology present the possibility for targeted therapy possibly decreasing the rate and severity of treatment-associated morbidity. Conclusions. Craniopharyngioma should be seen as a chronic disease. To achieve optimal outcomes a multidisciplinary team of specialized neurosurgeons, neuro-radiologists, neuro-oncologists, pathologists and endocrinologists should be involved in the diagnosis, planning of the surgery, irradiation and long-term follow-up. craniopharyngioma hypopituitarism metabolic syndrome kraniofaringiom hipopituitarizem presnovni sindrom true false true Association of Radiology and Oncology Ljubljana Angleški jezik Slovenski jezik by Authors Neznano 2024-07-09 13:09:10 2024-07-09 13:09:10 2024-07-10 03:52:52 0000-00-00 00:00:00 2019 0 0 Soavtorji: Soncka Jazbinsek, Roman Bosnjak, Mara Popovic, Lorna Zadravec Zaletel, Tina Vipotnik Vesnaver, Barbara Faganel Kotnik, Primoz Kotnik; str. 388-396, I no. 4 Vol. 53 dec. 2019 0000-00-00 Zaloznikova Objavljeno NiDoloceno 0000-00-00 0000-00-00 2019-12-01 616-006 1318-2099 10.2478/raon-2019-0036 34550489 https://content.sciendo.com/view/journals/raon/ahead-of-print/article-10.2478-raon-2019-0036.xml 1 acfecfef-3de3-11ef-b487-001a4af901a5 https://dirros.openscience.si/Dokument.php?lang=slv&id=26475 RAZ_Jensterle_Sever_Mojca_2019.pdf RAZ_Jensterle_Sever_Mojca_2019.pdf 1 468B251E5E1C022C66F4666EC6576980 409e595de7f198230d8a516bd1eb521135d61542f8b1596a936bc86588af2eb3 dcbe7593-3de3-11ef-b487-001a4af901a5 https://dirros.openscience.si/Dokument.php?lang=slv&id=26476 Onkološki inštitut Ljubljana 0 0 0