20.500.12556/DiRROS-18948 Environmental factors influence cross-talk between a heat shock protein and an oxidative stress protein modification in the lizard Gallotia galloti Better understanding how organisms respond to their abiotic environment, especially at the biochemical level, is critical in predicting population trajectories under climate change. In this study, we measured constitutive stress biomarkers and protein post-translational modifications associated with oxidative stress in Gallotia galloti, an insular lizard species inhabiting highly heterogeneous environments on Tenerife. Tenerife is a small volcanic island in a relatively isolated archipelago off the West coast of Africa. We found that expression of GRP94, a molecular chaperone protein, and levels of protein carbonylation, a marker of cellular stress, change across different environments, depending on solar radiation-related variables and topology. Here, we report in a wild animal population, cross-talk between the baseline levels of the heat shock protein-like GRP94 and oxidative damage (protein carbonylation), which are influenced by a range of available temperatures, quantified through modelled operative temperature. This suggests a dynamic trade-off between cellular homeostasis and oxidative damage in lizards adapted to this thermally and topologically heterogeneous environment. Gallotia galloti oksidativni stres proteomika metabolizem plazilci kuščarji zoologija ekologija oxidative stress proteomics metabolism reptiles lizards zoology ecology true false true Angleški jezik Slovenski jezik Neznano 2024-05-17 13:23:57 2024-05-17 13:23:58 2024-05-23 11:39:58 0000-00-00 00:00:00 2024 0 0 Nasl. z nasl. zaslona; Soavtorji: Anamarija Žagar, Marta López-Darias, Rodrigo Megía-Palma, Karen A. Lister, Max Dolton Jones, Miguel A. Carretero, Nina Serén, Pedro Beltran-Alvarez, Katharina C. Wollenberg Valero; Opis vira z dne 20. 3. 2024; Str. 1-21 [article no.] ǂe0300111 iss. 3 2024 0000-00-00 Zaloznikova Objavljeno apc 0000-00-00 0000-00-00 2024-03-12 591 1932-6203 10.1371/journal.pone.0300111 189630979 https://doi.org/10.1371/journal.pone.0300111 1 f6118ba0-143f-11ef-9c9e-001a4af901a5 https://dirros.openscience.si/Dokument.php?lang=slv&id=25975 RAZ_Gilbert_Edward_2024.pdf RAZ_Gilbert_Edward_2024.pdf 1 035DB8C458A7872158A05309A93B9589 2c49fa3d952628b03a502c4471c767b2ac1bb19ef2754e6e5fcf2e04c860e323 ae714905-1440-11ef-9c9e-001a4af901a5 https://dirros.openscience.si/Dokument.php?lang=slv&id=25976 Nacionalni inštitut za biologijo 0 0 0