20.500.12556/DiRROS-18657 Osteoblastic bone metastases from renal cell carcinoma Background. RCC accounts for only 2-3% of all cancers. Due to its non-specific symptoms disease is often diagnosed in advanced stage. Disseminated RCC frequently produces bone metastases that are almost always highly destructive, hyper vascularized and purely osteolytic. Case report. In this article we describe a case of a 71-year old male patient with disseminated osteoblastic bone metastases from renal cell carcinoma (RCC), and present a short review of published literature reporting cases of osteoblastic bone metastases from RCC. Our patient presented with thoracic pain aggravated by movement. He was diagnosed with predominantly osteoblastic bone metastases in the skeleton of thoracic and lumbar vertebra along with metastases in iliac bones, ribs, humerus and clavicles. Initially, origin of bone metastases was unknown, but later a small tumor in patients right kidney was identified. Microscopic evaluation of the open bone biopsy showed clear cell RCC with sarcomatoid differentiation. Conclusions. Although, due to its rarity, RCC is not included in the primary differential diagnosis in patients with osteoblastic metastases, such rare cases suggest that RCC may be considered in the diagnosis when there no other primary tumor is found. rak ledvic kostne metastaze osteoblasti true false true Association of Radiology and Oncology Ljubljana Angleški jezik Slovenski jezik by Authors Neznano 2024-04-11 09:24:03 2024-04-11 09:24:03 2024-04-12 03:37:20 0000-00-00 00:00:00 2014 0 0 str. 243-246 no. 3 Vol. 48 Sep. 2014 0000-00-00 Zaloznikova Objavljeno NiDoloceno 0000-00-00 0000-00-00 2014-09-01 616.6-006 1318-2099 10.2478/raon-2013-0034 1548923 RAZ_Salapura_Vladka_2014.pdf RAZ_Salapura_Vladka_2014.pdf 1 A42FC2BB2B61EB8C83477FD9A4E3EDBD 637d084a60cf7807c0e9de4f99478536ddd368b327817fda01983ff59de13bdd e8b2e73d-f7c3-11ee-ae20-001a4af901a5 https://dirros.openscience.si/Dokument.php?lang=slv&id=25487 Onkološki inštitut Ljubljana 0 0 0