20.500.12556/DiRROS-18032 Lymphangioleiomyomatosis Limfangioleiomiomatoza Background. Lymphangioleiomyomatosis is a rare disease of unknown origin, which affects women in their reproductive period. It is characterised by non-neoplastic proliferation of atypical smooth muscle cells in the lung parenchyma, lymphatic vessels and mediastinal and abdominal lymph nodes. The most common presenting symptoms are spontaneous pneumothorax, dyspnea, hemoptysis and chylothorax. Conclusions. High-resolution computed tomography (HRCT) and open lung biopsy followed by the immunohistologic studies are two diagnostic procedures with which diagnosis can be confirmed. Various treatmentmodalities are applied, particularly hormonal therapy, though their efficacy remain unknown. The prognosis of patients is bad. lzhodišča. Limfangioleiomiomatoza je redka bolezen neznanega vzroka, za katerozbolevajo ženske v rodnem obdobju. Za bolezen je značilna neneoplastičnaproliferacija atipičnih gladkomišičnih celic v pljučnem parenhimu, limfnih žilah ter mediastinalnih in abdominalnih bezgavkah. V klinični sliki se pojavljajo spontani pnevmotoraksi, dispneja, hemoptize in hilotoraks. Zaključlti. Računalniška tomografija visoke ločljivosti in imunohistološke metode v bioptičnih vzorcih pljučnega tkiva nam omogočajo pravilno postavitev diagnoze. Načini zdravljenja so različni, običajno hormonski, vendar je zaenkrat njihov uspeh še vprašljiv, prognoza bolnikov pa slaba. true false true Slovenian Medical Association - Slovenian Association of Radiology, Nuclear Medicine Society, Slovenian Society far Radiotherapy and Oncology, and Slovenian Cancer Society Ljubljana Angleški jezik Slovenski jezik by Authors Neznano 2024-01-31 09:20:36 2024-01-31 09:20:36 2024-02-01 03:40:46 0000-00-00 00:00:00 2002 0 0 BSDOCID88061; str. 41-46 št. 1 Letn. 36 2002 0000-00-00 Zaloznikova Objavljeno NiDoloceno 0000-00-00 0000-00-00 2002-01-01 616-006 1318-2099 14747865 RAZ_Anderluh_Franc_2002.pdf RAZ_Anderluh_Franc_2002.pdf 1 74F24D1D943B2DD173A37FB306561B00 15f7a102e99500df0a1987cd349d97bfee4ebf6f7e9c61412a34f050104dbc6f c4c96bd6-c011-11ee-b0d4-001a4af901a5 https://dirros.openscience.si/Dokument.php?lang=slv&id=24472 Onkološki inštitut Ljubljana 0 0 0