20.500.12556/DiRROS-17983 Electrochemotherapy with cisplatin of breast cancer tumor modules in a male patient Elektrokemoterapija s cisplatinom pri bolniku z rakom dojke Background. The metastases of breast cancer in a male patient were treated with electrochemotherapy by intratumoral injection of cisplatin. Electrochemotherapy is chemotherapy with the subsequent local application of electric pulses to the tumor nodules in order to increase drug delivery into the cells. Case report. Cutaneous metastases of breast cancer were treated with the intratumoral administration of cisplatin and by 8 electric pulses (1300 V/cm) applied a minute later to each cutaneous metastasis. The treatmentresulted in complete response of two electrochemotherapy treated cutaneous metastases and partial response of the third metastasis. In cutaneous metastases treated with intratumoral administartion of cisplatin without electric pulses, only partial response was obtained. Conclusion. This study confirms that electrochemotherapy with cisplatin is effective in the treatment of breast cancer metastases, too, as it was already proved for electrochemotherapy with bleomycin. Izvleček. Avtorji so zdravili kožne metastaze pri bolniku z rakom dojke z elektrokemoterapijo s cisplatinom. Elektrokemoterapija je zdravljenje s kemoterapijo, ki ji sledi lokalna aplikacija električnih pulzov na tumorske lezije; električni pulzi povečajo vnos kemoterapevtika v celice. Prikaz primera. Avtorji so zdravili kožne metastaze raka dojke z intratumorsko aplikacijo cisplatina in 8 električnimi pulzi, ki so jih na vsako kožno metastazo aplicirali 1 minuto po vnosu cisplatina. Pri zdravljenju z elektrokemoterapijo so pri dveh kožnih metastazah dosegli popolni odgovor, pri1 kožni metastazi pa delni odgovor. Pri kožnih metastazah, ki so jih zdravili samo z intratumorsko aplikacijo cispatina, pa so dosegli le delni odgovor. Zaključek. Elektrokemoterapija s cisplatinom je tako kot elektrokemoterapija z bleomicinom učinkovita pri zdravljenju kožnih metastaz raka na dojk. true false true Slovenian Medical Association - Slovenian Association of Radiology, Nuclear Medicine Society, Slovenian Society far Radiotherapy and Oncology, and Slovenian Cancer Society Ljubljana Angleški jezik Slovenski jezik by Authors Neznano 2024-01-25 09:48:47 2024-01-25 09:48:47 2024-01-26 03:50:47 0000-00-00 00:00:00 2000 0 0 BSDOCID56903; str. 357-361 št. 4 Letn. 34 2000 0000-00-00 Zaloznikova Objavljeno NiDoloceno 0000-00-00 0000-00-00 2000-01-01 616-006 1318-2099 12586457 RAZ_Rebersek_Martina_2000.pdf RAZ_Rebersek_Martina_2000.pdf 1 0BAF370B55486EB6CDF1A0384159F874 cfca6dda0b3819227942f9359d5f7a05768eb68b6c171c1856f8fa670830bc5c bb06cd21-bb5e-11ee-b0d4-001a4af901a5 https://dirros.openscience.si/Dokument.php?lang=slv&id=24393 Onkološki inštitut Ljubljana 0 0 0