20.500.12556/DiRROS-17868 Cytology of mediastinal tumors [Citologija mediastinalnih tumorjev] Our experience with cytological examinations of tumorous mediastinal lesions is evaluated. A group of 117 patients with mediastinal tumor have been included into the study. Among them carcinomas prevailed (60,7%), followed by lymphomas (18,8%), other tumors (15.4%) and thymic neoplasms (5.1%). Malignantor suspicious cells were found in 77.4% of patients with carcinoma. The cells indicating a possibility of non-Hodgkin's lymphoma were found in 9 out of 14 patients. In 5 out of 6 thymic neoplasms the cytological pattern wasconsistent with the diagnosis of thymic neoplasm. One case of thymoma was cytologically falsely diagnosed as malignant lymphoma. One case of neurofibroma was falsely diagnosed as adenocarcinoma. The sensitivity of cytological examinations was 67.5%. If 18 patients with diagnostically unsatisfactory material were excluded from the analysis, the sensitivity wouldincrease to 80.8%. Owing to the wide variety of primary and metastatic tumors that can occur in the mediastinum, apart from the routine cytological techniques, additional staining methods should be used. For final cytological diagnosis the integration of cytological findings with clinical and radiological data is often required. Owing to the characteristics of the obtained material and biological behaviour of some mediastinal tumors, some tumors cannot be definitively diagnosed by cytological examinations alone. Avtorji predstavijo izkušnje Kliničnega oddelka za pljučne bolezni in alergična stanja Golnik s citološkimi pregledi mediastinalnih tumorjev. V retrospektivno študijo je bilo vključenih 117 bolnikov z mediastinalnim tumorjem. Najpogostejši so bili karcinomi (60,7%0, sledijo limfomi (18,8%), drugi tumorji (15,4%), in timične neoplazme (5,1%). Maligne ali sunljive celice so našli pri 77,4% bolnikov s karcinomom. Celice, ki so dopuščale možnost ne-Hodgkinovega limfoma, so našli pri 9 od 14 bolnikov. Pri 5 od 6 primerov timičnih neplazem je bila citološka slika skladna z diagnozo timične neoplazme. En primer timoma je bil citološko napačno opredeljen kot maligni limfom, en primer neurofibroma pa je bil napačno opredeljen kot adenokarcinom.Senzitivnost citoloških pregledov je bila 67,5%. Če bi 18 bolnikov, pri katerih dobljeni material ni bil ustrezen, izključili iz analize, bi senzitivnost zrasla na 80,8%. Ker so primarni in metastatski tumorji, ki se pojavljajo v mediastinumu zelo raznoliki, so za njihovo opredelitev poleg rutinskih citoloških tehnik potrebne tudi dodatne metode barvanja. Za končno citološko diagnozo je nujno poznati tudi klinične podatke in podatke slikovnih diagnostičnih metod. Glede na značilnosti dobljenjega materiala in biološko obnašanje nekaterih mediastinalnih tumorjev vseh ni možno definitivno opredeliti na osnovi citološkega pregleda. true false true Slovenian Medical Society - Section of Radiology ; Croatian Medical Association - Croatian Society of Radiology Ljubljana Angleški jezik Slovenski jezik by Authors Neznano 2024-01-18 10:29:11 2024-01-18 10:29:11 2024-01-19 03:36:21 0000-00-00 00:00:00 1997 0 0 BSDOCID35243; str. 380-383 št. 4 Letn. 31 1997 0000-00-00 Zaloznikova Objavljeno NiDoloceno 0000-00-00 0000-00-00 1997-01-01 616-006 1318-2099 7829465 RAZ_Mermolja_Milivoj_1997.pdf RAZ_Mermolja_Milivoj_1997.pdf 1 7A5A3781DB04B5785F8493D0CBE2F848 3cb87b8249a99d11c3eda6c3d747e1e50a74378358e97848ea3d38f78af8ba50 35e8e0e4-b5e4-11ee-b0d4-001a4af901a5 https://dirros.openscience.si/Dokument.php?lang=slv&id=24230 Onkološki inštitut Ljubljana 0 0 0