20.500.12556/DiRROS-14429 Reduced parasympathetic reactivation during recovery from exercise in myalgic encephalomyelitis/chronic fatigue syndrome Although autonomic nervous system (ANS) dysfunction in Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS) has been proposed, conflicting evidence makes it difficult to draw firm conclusions regarding ANS activity at rest in ME/CFS patients. Although severe exercise intolerance is one of the core features of ME/CFS, little attempts have been made to study ANS responses to physical exercise. Therefore, impairments in ANS activation at rest and following exercise were examined using a case-control study in 20 ME/CFS patients and 20 healthy people. Different autonomous variables, including cardiac, respiratory, and electrodermal responses were assessed at rest and following an acute exercise bout. At rest, parameters in the time-domain represented normal autonomic function in ME/CFS, while frequency-domain parameters indicated the possible presence of diminished (para)sympathetic activation. Reduced parasympathetic reactivation during recovery from exercise was observed in ME/CFS. This is the first study showing reduced parasympathetic reactivation during recovery from physical exercise in ME/CFS. Delayed HR recovery and/or a reduced HRV as seen in ME/CFS have been associated with poor disease prognosis, high risk for adverse cardiac events, and morbidity in other pathologies, implying that future studies should examine whether this is also the case in ME/CFS and how to safely improve HR recovery in this population. autonomic nervous system autonomic function electrodermal activity electrocardiogram heart rate physical activity živčevje živčni sistem elektrodermalna aktivnost elektrokardiogram srčni utrip telesna aktivnost true false true Angleški jezik Ni določen 2021 by the authors Neznano 2021-10-20 13:24:04 2021-10-20 13:24:05 2022-08-20 03:35:28 0000-00-00 00:00:00 2021 0 0 Nasl. z nasl. zaslona; Soavtorji: Uros Marusic, Inge De Wandele, Mira Meeus, Lorna Paul, Luc Lambrecht, Greta Moorkens, Lieven Danneels, Jo Nijs; Opis vira z dne 19. 10. 2021; Članek št. 4527; str. 1-19 iss. 19 Vol. 10 Oct. 2021 0000-00-00 Zaloznikova Objavljeno NiDoloceno 0000-00-00 0000-00-00 0000-00-00 616.8:796.01 2077-0383 10.3390/jcm10194527 81462787 ZRSKP_Van_Oosterwijck_Jessica_i2021.pdf ZRSKP_Van_Oosterwijck_Jessica_i2021.pdf 1 D9784C996E36F0952206658BEDD4EDBE ef1c11b4c9e68c21fb6d466e789a63843266dd08e49344511b269a8e1b8fb275 b4f92467-17b6-11ed-b6b8-001a4af901a5 https://dirros.openscience.si/Dokument.php?lang=slv&id=18255 https://www.mdpi.com/2077-0383/10/19/4527 1 https://dirros.openscience.si/Dokument.php?lang=slv&id=18254 https://doi.org/10.3390/jcm10194527 1 https://dirros.openscience.si/Dokument.php?lang=slv&id=20274 Znanstveno-raziskovalno središče Koper / Centro di Ricerche Scientifiche Capodistria 0 0 0