20.500.12556/DiRROS-12632 Continuous glucose monitoring use and glucose variability in pre-school children with type 1 diabetes Aims. The objective of this nationwide population-based cohort study was to evaluate the correlation between continuous glucose monitoring (CGM) use and glucose variability in pre-schoolers with type 1 diabetes. Methods. We analysed data from the Slovenian National Registry. The primary endpoint was the difference in glucose variability between periods, during which participants were using CGM and periods, during which CGM was not used, over 5 years. Results. A total of 40 children <8 years old were followed for an estimated observational period of 116 patient/years. Mean age at CGM initiation was 3.5 (±1.7) years. Both standard deviation of mean glucose [3.6 mmol/L (3.2–3.9) with CGM and 4.3 mmol/L (3.8–4.7) without CGM, p < 0.001] and coefficient of variation [44.0% (40.4–47.0) with CGM and 46.1% (42.3–49.4) without CGM, p = 0.021] were lower during the periods, when CGM was used. Frequent CGM use (>5 days/week) was associated with a 0.4% [4.4 mmol/mol] reduction in glycated haemoglobin level (7.6% compared to 7.2%, p = 0.047). Conclusions. Our results indicate that the use of CGM was associated with reduced glucose variability during a 5 year follow-up period among pre-schoolers with type 1 diabetes. continuous glucose monitoring type 1 diabetes children insulin therapy true false true Elsevier Angleški jezik Ni določen © 2018 The Authors Neznano 2020-11-12 14:32:29 2020-11-12 14:32:29 2022-08-18 03:38:28 0000-00-00 00:00:00 2018 0 Nizozemska 0 str. 76-80 Vol. 147 Jan. 2019 0000-00-00 Zaloznikova Objavljeno NiDoloceno 0000-00-00 0000-00-00 0000-00-00 616.379 0168-8227 10.1016/j.diabres.2018.10.005 5261484 530708 RAZ_Dovc_Klemen_i2018.pdf RAZ_Dovc_Klemen_i2018.pdf 1 A2DB755CCE7EB20130CAE7E91A864D81 89aa5d93e3a86316a5dd235e548961b0b59172e772c914703d3c2225160bcc0f 88132791-17b6-11ed-b6b8-001a4af901a5 https://dirros.openscience.si/Dokument.php?lang=slv&id=17208 https://www.sciencedirect.com/science/article/pii/S0168822718310878?via%3Dihub 1 https://dirros.openscience.si/Dokument.php?lang=slv&id=15357 Univerzitetna klinika za pljučne bolezni in alergijo Golnik 0 0 0