20.500.12556/DiRROS-12302 Towards personalization of asthma treatment according to trigger factors Asthma is a severe and chronic disabling disease affecting more than 300 million people world-wide. While in the past few drugs for treatment of asthma were available, new treatment options are currently emerging which appear to be highly effective in certain subgroups of patients. Accordingly there is a need for biomarkers which allow selection of patients for refined and personalized treatment strategies. Recently, serological chip tests based on micro-arrayed allergen molecules and peptides derived from the most common rhinovirus strains have been developed which may discriminate two of the most common forms of asthma, i.e., allergen- and virus-triggered asthma. In this perspective we argue that classification of asthma patients according to these common trigger factors may open new possibilities for personalized management of asthma. allergy and immunology asthma signs and symptoms respiratory rhinovirus allergens microarray analysis precision medicine wheeze alergija in imunologija astma respiratorni znaki in simptomi rinovirus alergeni analiza mikromrež personalizirana medicina sopenje true false true Elsevier Inc. Angleški jezik Ni določen 2020 The Authors Neznano 2020-07-31 12:56:49 2020-07-31 12:56:49 2022-08-18 03:36:31 0000-00-00 00:00:00 2020 0 ZDA 0 Nasl. z nasl. zaslona; Soavtorica iz Slovenije: Mihaela Zidarn; Opis vira z dne 28. 2. 2020; str. 1529-1534 iss. 6 Vol. 145 Jun. 2020 0000-00-00 Zaloznikova Objavljeno NiDoloceno 0000-00-00 0000-00-00 0000-00-00 616-097 1097-6825 10.1016/j.jaci.2020.02.001 2048639089 3614228 RAZ_Niespodziana_Katarzyna_i2020.pdf RAZ_Niespodziana_Katarzyna_i2020.pdf 1 7E21FD21CA8F771F802094489AE174FD 3619409acc12024c748270a0a51d41961e0035fb66ecdfde4b51fb455ddbeccf 8e6d2838-17b6-11ed-b6b8-001a4af901a5 https://dirros.openscience.si/Dokument.php?lang=slv&id=17321 https://www.jacionline.org/article/S0091-6749(20)30193-7/pdf 1 https://dirros.openscience.si/Dokument.php?lang=slv&id=14826 Univerzitetna klinika za pljučne bolezni in alergijo Golnik 0 0 0