Impact of CT tube voltage and anode current on PET/CT image qualityČavlin, Milana (Avtor) Ležaič, Luka (Avtor) Rep, Sebastijan (Avtor) PET/CTstandardized uptake valuequantificationdose optimizationimage qualitytube voltageanode currentPositron emission tomography/computer tomography is a crucial modality for the quantification of metabolic activity and anatomical structure. Reducing radiation dose, especially in repeated imaging, remains a significant challenge. This study focuses on optimizing computer tomography parameters to reduce dose, while maintaining image quality. The aim of this research was to determine the impact of varying computer tomography tube voltage and anode current, on the quantification of standardized uptake value, contrast-to-noise ratio, and radiation exposure (volume CT dose index, dose-length product). A NEMA IQ body phantom was scanned using various combinations of tube voltage and anode current. Standardized up-take value, contrast-to-noise ratio, volume CT dose index and dose-length product, were evaluated from the different scans. The obtained results were statistically assessed. Reducing tube voltage and anode current did not significantly affect standardized uptake value accuracy but, reduced radiation dose. Image quality (contrast-to-noise ratio) remained diagnostically acceptable, supporting the potential for optimization without compromising accuracy. Optimization of computer tomography parameters (tube voltage, anode current) is feasible and beneficial in clinical practice, as it reduces patient radiation burden while maintaining image quality and standardized uptake value accuracy.20262026-08-06 09:09:57Neznano31682UDK: 61ISSN pri članku: 1452-8185DOI: 10.2298/NTRP2602152CCOBISS_ID: 286409987slNa spletni strani revije navedeno: Nuclear Technology & Radiation Protection is an open access Journal. All articles can be downloaded free of charge and used in accordance with the Creative Commons Attribution-NonCommercial-NoDerivatives 3.0 Serbia (https://ntrp.vinca.rs/Editorial%20policy.htm)