Robot-assisted radical prostatectomy after RezūmCerović, Kosta (Avtor) Hawlina, Simon (Avtor) prostate cancerrobotic surgeryrobot-assisted radical prostatectomyRARPRezumbenign prostatic obstructionBPOintraoperative fibrosisminimally invasive surgical therapiesMISTsMinimally invasive surgical therapies (MISTs), such as Rezum¯ ™ Water Vapor Therapy, are emerging treatment options for benign prostatic obstruction (BPO). When prostate cancer is subsequently diagnosed, radical prostatectomy may still be indicated. However, evidence regarding intraoperative challenges and the surgical and functional outcomes of robot-assisted radical prostatectomy (RARP) following Rezum remains limited. We ¯ report the first documented case of RARP following Rezum in a 68-year-old man. He ¯ initially underwent Rezum for symptomatic BPO. Due to rising PSA, a suspicious lesion on ¯ MRI, and a biopsy-confirmed high-risk prostate carcinoma, radical surgery was performed. Intraoperatively, dense fibrosis and altered tissue planes required precise dissection and a level 2 bilateral nerve-sparing approach. A systematic review revealed no previously published cases of RARP after Rezum. On the other hand, RARP after transurethral ¯ resection of the prostate (TURP) is associated with increased operative time, blood loss, and bladder neck reconstruction, though late continence and biochemical recurrence rates are similar to those in treatment-naïve patients. In conclusion, RARP after ablative BPO therapies is feasible but may present unique technical challenges. Larger prospective studies are needed to develop standardized management strategies.20262026-04-08 15:29:13Neznano28832sl