Comparative epidemiology of suspected perioperative hypersensitivity reactionsMertes, Paul Michel (Avtor) Ebo, Didier G. (Avtor) Garcez, Tomaz (Avtor) Rose, Michael (Avtor) Sabato, Vito (Avtor) Takazawa, Tomonori (Avtor) Cooke, Peter J. (Avtor) Clarke, Russel C. (Avtor) Dewachter, Pascale (Avtor) Garvey, Lene Heise (Avtor) Guttormsen, Anne Berit (Avtor) Hepner, David L. (Avtor) Hopkins, Philip M. (Avtor) Khan, David A. (Avtor) Kopač, Peter (Avtor) Platt, Peter R. (Avtor) Savic, Louise C. (Avtor) anaphylaxisanti-bacterial agentsbloodchlorhexidinelatexneuromuscular blocking agentshypersensitivitydrug hypersensitivitysugammadexantibioticsblood productsperioperative anaphylaxisperioperative hypersensitivitySuspected perioperative hypersensitivity reactions are rare but contribute significantly to the morbidity and mortality of surgical procedures. Recent publications have highlighted the differences between countries concerning the respective risk of different drugs, and changes in patterns of causal agents and the emergence of new allergens. This review summarises recent information on the epidemiology of perioperative hypersensitivity reactions, with specific consideration of differences between geographic areas for the most frequently involved offending agents.Elsevier20192020-10-16 12:33:25Neznano12588sl© 2019 Published by Elsevier Ltd on behalf of British Journal of Anaesthesia